Luckett JC - Search Results

1

Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis.

John AE, Graves RH, Pun KT, Vitulli G, Forty EJ, Mercer PF, Morrell JL, Barrett JW, Rogers RF, Hafeji M, Bibby LI, Gower E, Morrison VS, Man Y, Roper JA, Luckett JC, Borthwick LA, Barksby BS, Burgoyne RA, Barnes R, Le J, Flint DJ, Pyne S, Habgood A, Organ LA, Joseph C, Edwards-Pritchard RC, Maher TM, Fisher AJ, Gudmann NS, Leeming DJ, Chambers RC, Lukey PT, Marshall RP, Macdonald SJF, Jenkins RG, Slack RJ. John AE, et al. Among authors: luckett jc. Nat Commun. 2020 Sep 16;11(1):4659. doi: 10.1038/s41467-020-18397-6. Nat Commun. 2020. PMID: 32938936 Free PMC article.

2

Preclinical SPECT/CT imaging of αvβ6 integrins for molecular stratification of idiopathic pulmonary fibrosis.

John AE, Luckett JC, Tatler AL, Awais RO, Desai A, Habgood A, Ludbrook S, Blanchard AD, Perkins AC, Jenkins RG, Marshall JF. John AE, et al. Among authors: luckett jc. J Nucl Med. 2013 Dec;54(12):2146-52. doi: 10.2967/jnumed.113.120592. Epub 2013 Oct 28. J Nucl Med. 2013. PMID: 24167080 Free article.

3

Pharmacological characterisation of GSK3335103, an oral αvβ6 integrin small molecule RGD-mimetic inhibitor for the treatment of fibrotic disease.

Wilkinson AL, John AE, Barrett JW, Gower E, Morrison VS, Man Y, Pun KT, Roper JA, Luckett JC, Borthwick LA, Barksby BS, Burgoyne RA, Barnes R, Fisher AJ, Procopiou PA, Hatley RJD, Barrett TN, Marshall RP, Macdonald SJF, Jenkins RG, Slack RJ. Wilkinson AL, et al. Among authors: luckett jc. Eur J Pharmacol. 2021 Dec 15;913:174618. doi: 10.1016/j.ejphar.2021.174618. Epub 2021 Nov 8. Eur J Pharmacol. 2021. PMID: 34762934

4

[(18)F]FDG-6-P as a novel in vivo tool for imaging staphylococcal infections.

Mills B, Awais RO, Luckett J, Turton D, Williams P, Perkins AC, Hill PJ. Mills B, et al. EJNMMI Res. 2015 Mar 19;5:13. doi: 10.1186/s13550-015-0095-1. eCollection 2015. EJNMMI Res. 2015. PMID: 25853019 Free PMC article.

5

Antibody-Mediated Inhibition of the FGFR1c Isoform Induces a Catabolic Lean State in Siberian Hamsters.

Samms RJ, Lewis JE, Lory A, Fowler MJ, Cooper S, Warner A, Emmerson P, Adams AC, Luckett JC, Perkins AC, Wilson D, Barrett P, Tsintzas K, Ebling FJ. Samms RJ, et al. Among authors: luckett jc. Curr Biol. 2015 Nov 16;25(22):2997-3003. doi: 10.1016/j.cub.2015.10.010. Epub 2015 Nov 5. Curr Biol. 2015. PMID: 26549257 Free article.

6

Reduced adiposity attenuates FGF21 mediated metabolic improvements in the Siberian hamster.

Lewis JE, Samms RJ, Cooper S, Luckett JC, Perkins AC, Adams AC, Tsintzas K, Ebling FJP. Lewis JE, et al. Among authors: luckett jc. Sci Rep. 2017 Jun 26;7(1):4238. doi: 10.1038/s41598-017-03607-x. Sci Rep. 2017. PMID: 28652585 Free PMC article.

7

Antibody-Mediated Targeting of the FGFR1c Isoform Increases Glucose Uptake in White and Brown Adipose Tissue in Male Mice.

Lewis JE, Samms RJ, Cooper S, Luckett JC, Perkins AC, Dunbar JD, Smith DP, Emmerson PJ, Adams AC, Ebling FJP, Tsintzas K. Lewis JE, et al. Among authors: luckett jc. Endocrinology. 2017 Oct 1;158(10):3090-3096. doi: 10.1210/en.2017-00591. Endocrinology. 2017. PMID: 28938451 Free PMC article.

8

Whole-body and adipose tissue-specific mechanisms underlying the metabolic effects of fibroblast growth factor 21 in the Siberian hamster.

Lewis JE, Monnier C, Marshall H, Fowler M, Green R, Cooper S, Chiotellis A, Luckett J, Perkins AC, Coskun T, Adams AC, Samms RJ, Ebling FJP, Tsintzas K. Lewis JE, et al. Mol Metab. 2020 Jan;31:45-54. doi: 10.1016/j.molmet.2019.10.009. Epub 2019 Nov 9. Mol Metab. 2020. PMID: 31918921 Free PMC article.

9

A novel virulence strategy for Pseudomonas aeruginosa mediated by an autotransporter with arginine-specific aminopeptidase activity.

Luckett JC, Darch O, Watters C, Abuoun M, Wright V, Paredes-Osses E, Ward J, Goto H, Heeb S, Pommier S, Rumbaugh KP, Cámara M, Hardie KR. Luckett JC, et al. PLoS Pathog. 2012;8(8):e1002854. doi: 10.1371/journal.ppat.1002854. Epub 2012 Aug 23. PLoS Pathog. 2012. PMID: 22927813 Free PMC article.

10

Effect of adeno-associated virus (AAV)-mediated overexpression of PEPCK-M (Pck2) on Clenbuterol-induced muscle growth.

Loczenski-Brown DM, Jones S, Luckett J, Daniel Z, Brearley MC, Ebling FJP, Parr T, Brameld JM. Loczenski-Brown DM, et al. PLoS One. 2019 Jun 25;14(6):e0218970. doi: 10.1371/journal.pone.0218970. eCollection 2019. PLoS One. 2019. PMID: 31237922 Free PMC article.

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