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Page 1
Liver Pyruvate Kinase Promotes NAFLD/NASH in Both Mice and Humans in a Sex-Specific Manner.
Chella Krishnan K, Floyd RR, Sabir S, Jayasekera DW, Leon-Mimila PV, Jones AE, Cortez AA, Shravah V, Péterfy M, Stiles L, Canizales-Quinteros S, Divakaruni AS, Huertas-Vazquez A, Lusis AJ. Chella Krishnan K, et al. Among authors: stiles l. Cell Mol Gastroenterol Hepatol. 2021;11(2):389-406. doi: 10.1016/j.jcmgh.2020.09.004. Epub 2020 Sep 14. Cell Mol Gastroenterol Hepatol. 2021. PMID: 32942044 Free PMC article.
Etomoxir Inhibits Macrophage Polarization by Disrupting CoA Homeostasis.
Divakaruni AS, Hsieh WY, Minarrieta L, Duong TN, Kim KKO, Desousa BR, Andreyev AY, Bowman CE, Caradonna K, Dranka BP, Ferrick DA, Liesa M, Stiles L, Rogers GW, Braas D, Ciaraldi TP, Wolfgang MJ, Sparwasser T, Berod L, Bensinger SJ, Murphy AN. Divakaruni AS, et al. Among authors: stiles l. Cell Metab. 2018 Sep 4;28(3):490-503.e7. doi: 10.1016/j.cmet.2018.06.001. Epub 2018 Jun 28. Cell Metab. 2018. PMID: 30043752 Free PMC article.
Sex-specific metabolic functions of adipose Lipocalin-2.
Chella Krishnan K, Sabir S, Shum M, Meng Y, Acín-Pérez R, Lang JM, Floyd RR, Vergnes L, Seldin MM, Fuqua BK, Jayasekera DW, Nand SK, Anum DC, Pan C, Stiles L, Péterfy M, Reue K, Liesa M, Lusis AJ. Chella Krishnan K, et al. Among authors: stiles l. Mol Metab. 2019 Dec;30:30-47. doi: 10.1016/j.molmet.2019.09.009. Epub 2019 Sep 27. Mol Metab. 2019. PMID: 31767179 Free PMC article.
A novel approach to measure mitochondrial respiration in frozen biological samples.
Acin-Perez R, Benador IY, Petcherski A, Veliova M, Benavides GA, Lagarrigue S, Caudal A, Vergnes L, Murphy AN, Karamanlidis G, Tian R, Reue K, Wanagat J, Sacks H, Amati F, Darley-Usmar VM, Liesa M, Divakaruni AS, Stiles L, Shirihai OS. Acin-Perez R, et al. Among authors: stiles l. EMBO J. 2020 Jul 1;39(13):e104073. doi: 10.15252/embj.2019104073. Epub 2020 May 20. EMBO J. 2020. PMID: 32432379 Free PMC article.
Blocking mitochondrial pyruvate import in brown adipocytes induces energy wasting via lipid cycling.
Veliova M, Ferreira CM, Benador IY, Jones AE, Mahdaviani K, Brownstein AJ, Desousa BR, Acín-Pérez R, Petcherski A, Assali EA, Stiles L, Divakaruni AS, Prentki M, Corkey BE, Liesa M, Oliveira MF, Shirihai OS. Veliova M, et al. Among authors: stiles l. EMBO Rep. 2020 Dec 3;21(12):e49634. doi: 10.15252/embr.201949634. Epub 2020 Dec 4. EMBO Rep. 2020. PMID: 33275313 Free PMC article.
ABCB10 exports mitochondrial biliverdin, driving metabolic maladaptation in obesity.
Shum M, Shintre CA, Althoff T, Gutierrez V, Segawa M, Saxberg AD, Martinez M, Adamson R, Young MR, Faust B, Gharakhanian R, Su S, Chella Krishnan K, Mahdaviani K, Veliova M, Wolf DM, Ngo J, Nocito L, Stiles L, Abramson J, Lusis AJ, Hevener AL, Zoghbi ME, Carpenter EP, Liesa M. Shum M, et al. Among authors: stiles l. Sci Transl Med. 2021 May 19;13(594):eabd1869. doi: 10.1126/scitranslmed.abd1869. Sci Transl Med. 2021. PMID: 34011630 Free PMC article.
Sex-specific genetic regulation of adipose mitochondria and metabolic syndrome by Ndufv2.
Chella Krishnan K, Vergnes L, Acín-Pérez R, Stiles L, Shum M, Ma L, Mouisel E, Pan C, Moore TM, Péterfy M, Romanoski CE, Reue K, Björkegren JLM, Laakso M, Liesa M, Lusis AJ. Chella Krishnan K, et al. Among authors: stiles l. Nat Metab. 2021 Nov;3(11):1552-1568. doi: 10.1038/s42255-021-00481-w. Epub 2021 Oct 25. Nat Metab. 2021. PMID: 34697471 Free PMC article.
114 results