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Phase I clinical trial repurposing all-trans retinoic acid as a stromal targeting agent for pancreatic cancer.
Kocher HM, Basu B, Froeling FEM, Sarker D, Slater S, Carlin D, deSouza NM, De Paepe KN, Goulart MR, Hughes C, Imrali A, Roberts R, Pawula M, Houghton R, Lawrence C, Yogeswaran Y, Mousa K, Coetzee C, Sasieni P, Prendergast A, Propper DJ. Kocher HM, et al. Nat Commun. 2020 Sep 24;11(1):4841. doi: 10.1038/s41467-020-18636-w. Nat Commun. 2020. PMID: 32973176 Free PMC article. Clinical Trial.
Chronic pancreatitis.
Kocher HM, Froeling FE. Kocher HM, et al. BMJ Clin Evid. 2008 Dec 5;2008:0417. BMJ Clin Evid. 2008. PMID: 19445788 Free PMC article. Review.
Pancreatic cancer.
O'Sullivan A, Kocher HM. O'Sullivan A, et al. Among authors: kocher hm. BMJ Clin Evid. 2007 Nov 20;2007:0409. BMJ Clin Evid. 2007. PMID: 19450353 Review.
Pancreatic cancer organotypic cultures.
Froeling FE, Marshall JF, Kocher HM. Froeling FE, et al. Among authors: kocher hm. J Biotechnol. 2010 Jul 1;148(1):16-23. doi: 10.1016/j.jbiotec.2010.01.008. Epub 2010 Jan 18. J Biotechnol. 2010. PMID: 20083148 Review.
Imbalance of desmoplastic stromal cell numbers drives aggressive cancer processes.
Kadaba R, Birke H, Wang J, Hooper S, Andl CD, Di Maggio F, Soylu E, Ghallab M, Bor D, Froeling FE, Bhattacharya S, Rustgi AK, Sahai E, Chelala C, Sasieni P, Kocher HM. Kadaba R, et al. Among authors: kocher hm. J Pathol. 2013 May;230(1):107-17. doi: 10.1002/path.4172. Epub 2013 Mar 21. J Pathol. 2013. PMID: 23359139 Free PMC article.
Ezrin expression is an independent prognostic factor in gastro-intestinal cancers.
Arumugam P, Partelli S, Coleman SJ, Cataldo I, Beghelli S, Bassi C, Wijesuriya N, Aleong JA, Froeling FE, Scarpa A, Kocher HM. Arumugam P, et al. Among authors: kocher hm. J Gastrointest Surg. 2013 Dec;17(12):2082-91. doi: 10.1007/s11605-013-2384-1. Epub 2013 Oct 24. J Gastrointest Surg. 2013. PMID: 24155054
185 results