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Host sirtuin 1 regulates mycobacterial immunopathogenesis and represents a therapeutic target against tuberculosis.
Cheng CY, Gutierrez NM, Marzuki MB, Lu X, Foreman TW, Paleja B, Lee B, Balachander A, Chen J, Tsenova L, Kurepina N, Teng KWW, West K, Mehra S, Zolezzi F, Poidinger M, Kreiswirth B, Kaushal D, Kornfeld H, Newell EW, Singhal A. Cheng CY, et al. Among authors: singhal a. Sci Immunol. 2017 Mar;2(9):eaaj1789. doi: 10.1126/sciimmunol.aaj1789. Epub 2017 Mar 24. Sci Immunol. 2017. PMID: 28707004 Free PMC article.
NLRP10 Enhances CD4+ T-Cell-Mediated IFNγ Response via Regulation of Dendritic Cell-Derived IL-12 Release.
Vacca M, Böhme J, Zambetti LP, Khameneh HJ, Paleja BS, Laudisi F, Ho AWS, Neo K, Leong KWK, Marzuki M, Lee B, Poidinger M, Santambrogio L, Tsenova L, Zolezzi F, De Libero G, Singhal A, Mortellaro A. Vacca M, et al. Among authors: singhal a. Front Immunol. 2017 Nov 2;8:1462. doi: 10.3389/fimmu.2017.01462. eCollection 2017. Front Immunol. 2017. PMID: 29163529 Free PMC article.
Metformin Alters Human Host Responses to Mycobacterium tuberculosis in Healthy Subjects.
Lachmandas E, Eckold C, Böhme J, Koeken VACM, Marzuki MB, Blok B, Arts RJW, Chen J, Teng KWW, Ratter J, Smolders EJ, Van den Heuvel C, Stienstra R, Dockrell HM, Newell E, Netea MG, Singhal A, Cliff JM, Van Crevel R. Lachmandas E, et al. Among authors: singhal a. J Infect Dis. 2019 Jun 5;220(1):139-150. doi: 10.1093/infdis/jiz064. J Infect Dis. 2019. PMID: 30753544 Free PMC article.
Metformin enhances anti-mycobacterial responses by educating CD8+ T-cell immunometabolic circuits.
Böhme J, Martinez N, Li S, Lee A, Marzuki M, Tizazu AM, Ackart D, Frenkel JH, Todd A, Lachmandas E, Lum J, Shihui F, Ng TP, Lee B, Larbi A, Netea MG, Basaraba R, van Crevel R, Newell E, Kornfeld H, Singhal A. Böhme J, et al. Among authors: singhal a. Nat Commun. 2020 Oct 16;11(1):5225. doi: 10.1038/s41467-020-19095-z. Nat Commun. 2020. PMID: 33067434 Free PMC article.
Histone acetylome-wide associations in immune cells from individuals with active Mycobacterium tuberculosis infection.
Del Rosario RCH, Poschmann J, Lim C, Cheng CY, Kumar P, Riou C, Ong ST, Gerges S, Hajan HS, Kumar D, Marzuki M, Lu X, Lee A, Wijaya GC, Rayan NA, Zhuang Z, Du Bruyn E, Chee CBE, Lee B, Lum J, Zolezzi F, Poidinger M, Rotzschke O, Khor CC, Wilkinson RJ, Wang YT, Chandy GK, De Libero G, Singhal A, Prabhakar S. Del Rosario RCH, et al. Among authors: singhal a. Nat Microbiol. 2022 Feb;7(2):312-326. doi: 10.1038/s41564-021-01049-w. Epub 2022 Jan 31. Nat Microbiol. 2022. PMID: 35102304 Free PMC article.
Author Correction: Histone acetylome-wide associations in immune cells from individuals with active Mycobacterium tuberculosis infection.
Del Rosario RCH, Poschmann J, Lim C, Cheng CY, Kumar P, Riou C, Ong ST, Gerges S, Hajan HS, Kumar D, Marzuki M, Lu X, Lee A, Wijaya GC, Rayan NA, Zhuang Z, Du Bruyn E, Chee CBE, Lee B, Lum J, Zolezzi F, Poidinger M, Rotzschke O, Khor CC, Wilkinson RJ, Wang YT, Chandy GK, De Libero G, Singhal A, Prabhakar S. Del Rosario RCH, et al. Among authors: singhal a. Nat Microbiol. 2022 Nov;7(11):1943. doi: 10.1038/s41564-022-01236-3. Nat Microbiol. 2022. PMID: 36056160 Free PMC article. No abstract available.
1,417 results