O'Donnell KA - Search Results

1

eIF5B drives integrated stress response-dependent translation of PD-L1 in lung cancer.

Suresh S, Chen B, Zhu J, Golden RJ, Lu C, Evers BM, Novaresi N, Smith B, Zhan X, Schmid V, Jun S, Karacz CM, Peyton M, Zhong L, Wen Z, Sathe AA, Xing C, Behrens C, Wistuba II, Xiao G, Xie Y, Fu YX, Minna JD, Mendell JT, O'Donnell KA. Suresh S, et al. Nat Cancer. 2020 May;1(5):533-545. doi: 10.1038/s43018-020-0056-0. Epub 2020 Apr 20. Nat Cancer. 2020. PMID: 32984844 Free PMC article.

2

c-Myc-regulated microRNAs modulate E2F1 expression.

O'Donnell KA, Wentzel EA, Zeller KI, Dang CV, Mendell JT. O'Donnell KA, et al. Nature. 2005 Jun 9;435(7043):839-43. doi: 10.1038/nature03677. Nature. 2005. PMID: 15944709 Free article.

3

PROTOCADHERIN 7 Acts through SET and PP2A to Potentiate MAPK Signaling by EGFR and KRAS during Lung Tumorigenesis.

Zhou X, Updegraff BL, Guo Y, Peyton M, Girard L, Larsen JE, Xie XJ, Zhou Y, Hwang TH, Xie Y, Rodriguez-Canales J, Villalobos P, Behrens C, Wistuba II, Minna JD, O'Donnell KA. Zhou X, et al. Cancer Res. 2017 Jan 1;77(1):187-197. doi: 10.1158/0008-5472.CAN-16-1267-T. Epub 2016 Nov 7. Cancer Res. 2017. PMID: 27821484 Free PMC article.

4

SRC-2-mediated coactivation of anti-tumorigenic target genes suppresses MYC-induced liver cancer.

Suresh S, Durakoglugil D, Zhou X, Zhu B, Comerford SA, Xing C, Xie XJ, York B, O'Donnell KA. Suresh S, et al. PLoS Genet. 2017 Mar 8;13(3):e1006650. doi: 10.1371/journal.pgen.1006650. eCollection 2017 Mar. PLoS Genet. 2017. PMID: 28273073 Free PMC article.

5

Modulation of Mutant Kras^G12D -Driven Lung Tumorigenesis In Vivo by Gain or Loss of PCDH7 Function.

Zhou X, Padanad MS, Evers BM, Smith B, Novaresi N, Suresh S, Richardson JA, Stein E, Zhu J, Hammer RE, O'Donnell KA. Zhou X, et al. Mol Cancer Res. 2019 Feb;17(2):594-603. doi: 10.1158/1541-7786.MCR-18-0739. Epub 2018 Nov 8. Mol Cancer Res. 2019. PMID: 30409919 Free PMC article.

6

Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism.

Updegraff BL, Zhou X, Guo Y, Padanad MS, Chen PH, Yang C, Sudderth J, Rodriguez-Tirado C, Girard L, Minna JD, Mishra P, DeBerardinis RJ, O'Donnell KA. Updegraff BL, et al. Cell Rep. 2018 Nov 20;25(8):2223-2233.e6. doi: 10.1016/j.celrep.2018.10.100. Cell Rep. 2018. PMID: 30463017 Free PMC article.

7

Ex Vivo Transposon-Mediated Genetic Screens for Cancer Gene Discovery.

O'Donnell KA, Guo Y, Suresh S, Updegraff BL, Zhou X. O'Donnell KA, et al. Methods Mol Biol. 2019;1907:145-157. doi: 10.1007/978-1-4939-8967-6_12. Methods Mol Biol. 2019. PMID: 30542998 Free PMC article.

8

Translational Control of Immune Evasion in Cancer.

Suresh S, O'Donnell KA. Suresh S, et al. Trends Cancer. 2021 Jul;7(7):580-582. doi: 10.1016/j.trecan.2021.04.002. Epub 2021 May 7. Trends Cancer. 2021. PMID: 33972197 Free PMC article.

9

Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model.

Kota J, Chivukula RR, O'Donnell KA, Wentzel EA, Montgomery CL, Hwang HW, Chang TC, Vivekanandan P, Torbenson M, Clark KR, Mendell JR, Mendell JT. Kota J, et al. Cell. 2009 Jun 12;137(6):1005-17. doi: 10.1016/j.cell.2009.04.021. Cell. 2009. PMID: 19524505 Free PMC article.

10

Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis.

Guo Y, Updegraff BL, Park S, Durakoglugil D, Cruz VH, Maddux S, Hwang TH, O'Donnell KA. Guo Y, et al. Cancer Res. 2016 Feb 15;76(4):773-86. doi: 10.1158/0008-5472.CAN-15-1697. Epub 2015 Dec 16. Cancer Res. 2016. PMID: 26676752

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