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Triggering interferon signaling in T cells with avadomide sensitizes CLL to anti-PD-L1/PD-1 immunotherapy.
Ioannou N, Hagner PR, Stokes M, Gandhi AK, Apollonio B, Fanous M, Papazoglou D, Sutton LA, Rosenquist R, Amini RM, Chiu H, Lopez-Girona A, Janardhanan P, Awan FT, Jones J, Kay NE, Shanafelt TD, Tallman MS, Stamatopoulos K, Patten PEM, Vardi A, Ramsay AG. Ioannou N, et al. Blood. 2021 Jan 14;137(2):216-231. doi: 10.1182/blood.2020006073. Blood. 2021. PMID: 33024998 Free PMC article.
T-Cell Dynamics in Chronic Lymphocytic Leukemia under Different Treatment Modalities.
Vardi A, Vlachonikola E, Papazoglou D, Psomopoulos F, Kotta K, Ioannou N, Galigalidou C, Gemenetzi K, Pasentsis K, Kotouza M, Koravou E, Scarfó L, Iskas M, Stavroyianni N, Ghia P, Anagnostopoulos A, Kouvatsi A, Ramsay AG, Stamatopoulos K, Chatzidimitriou A. Vardi A, et al. Among authors: ioannou n. Clin Cancer Res. 2020 Sep 15;26(18):4958-4969. doi: 10.1158/1078-0432.CCR-19-3827. Epub 2020 Jul 2. Clin Cancer Res. 2020. PMID: 32616500
Gene-edited healthy donor CAR T cells show superior anti-tumour activity compared to CAR T cells derived from patients with lymphoma in an in vivo model of high-grade lymphoma.
Graham CE, Jozwik A, Quartey-Papafio R, Ioannou N, Metelo AM, Scala C, Dickson G, Stewart O, Almena-Carrasco M, Peranzoni E, Ramsay AG, Patten PEM, Pertel T, Farzaneh F, Dupouy S, Pepper A, Benjamin R. Graham CE, et al. Among authors: ioannou n. Leukemia. 2021 Dec;35(12):3581-3584. doi: 10.1038/s41375-021-01324-z. Epub 2021 Jun 18. Leukemia. 2021. PMID: 34145373 Free PMC article. No abstract available.
Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity.
Hanna BS, Llaó-Cid L, Iskar M, Roessner PM, Klett LC, Wong JKL, Paul Y, Ioannou N, Öztürk S, Mack N, Kalter V, Colomer D, Campo E, Bloehdorn J, Stilgenbauer S, Dietrich S, Schmidt M, Gabriel R, Rippe K, Feuerer M, Ramsay AG, Lichter P, Zapatka M, Seiffert M. Hanna BS, et al. Among authors: ioannou n. Immunity. 2021 Dec 14;54(12):2825-2841.e10. doi: 10.1016/j.immuni.2021.11.004. Epub 2021 Dec 7. Immunity. 2021. PMID: 34879221 Free article.
90 results