Shen JS - Search Results

1

Pharmacokinetics and tissue distribution of remdesivir and its metabolites nucleotide monophosphate, nucleotide triphosphate, and nucleoside in mice.

Hu WJ, Chang L, Yang Y, Wang X, Xie YC, Shen JS, Tan B, Liu J. Hu WJ, et al. Among authors: shen js. Acta Pharmacol Sin. 2021 Jul;42(7):1195-1200. doi: 10.1038/s41401-020-00537-9. Epub 2020 Oct 12. Acta Pharmacol Sin. 2021. PMID: 33041326 Free PMC article.

2

Nucleoside Inhibitors of Hepatitis C Virus NS5B Polymerase: A Systematic Review.

Xie Y, Ogah CA, Jiang X, Li J, Shen J. Xie Y, et al. Curr Drug Targets. 2016;17(13):1560-76. doi: 10.2174/1389450117666151209123751. Curr Drug Targets. 2016. PMID: 26648061 Review.

3

Synthesis, structure-activity relationships, and biological evaluation of a series of benzamides as potential multireceptor antipsychotics.

Yang F, Jiang X, Li J, Wang Y, Liu Y, Bi M, Wu C, Zhao Q, Chen W, Yin J, Zhang J, Xie Y, Hu T, Xu M, Guo S, Wang Z, He Y, Shen J. Yang F, et al. Bioorg Med Chem Lett. 2016 Jul 1;26(13):3141-3147. doi: 10.1016/j.bmcl.2016.04.087. Epub 2016 Apr 30. Bioorg Med Chem Lett. 2016. PMID: 27173799

4

Synthesis and biological investigation of tetrahydropyridopyrimidinone derivatives as potential multireceptor atypical antipsychotics.

Xiamuxi H, Wang Z, Li J, Wang Y, Wu C, Yang F, Jiang X, Liu Y, Zhao Q, Chen W, Zhang J, Xie Y, Hu T, Xu M, Guo S, Akber Aisa H, He Y, Shen J. Xiamuxi H, et al. Bioorg Med Chem. 2017 Sep 1;25(17):4904-4916. doi: 10.1016/j.bmc.2017.07.040. Epub 2017 Jul 24. Bioorg Med Chem. 2017. PMID: 28774576

5

Discovery of pyrimidine nucleoside dual prodrugs and pyrazine nucleosides as novel anti-HCV agents.

Guo S, Xu M, Guo Q, Zhu F, Jiang X, Xie Y, Shen J. Guo S, et al. Bioorg Med Chem. 2019 Mar 1;27(5):748-759. doi: 10.1016/j.bmc.2019.01.007. Epub 2019 Jan 16. Bioorg Med Chem. 2019. PMID: 30683552

6

Continuation of structure-activity relationship study of novel benzamide derivatives as potential antipsychotics.

Xu M, Guo S, Yang F, Wang Y, Wu C, Jiang X, Zhao Q, Chen W, Tian G, Zhu F, Xie Y, Hu T, Wang Z, He Y, Shen J. Xu M, et al. Arch Pharm (Weinheim). 2019 Apr;352(4):e1800306. doi: 10.1002/ardp.201800306. Epub 2019 Jan 31. Arch Pharm (Weinheim). 2019. PMID: 30702760

7

Synthesis of CBD and Its Derivatives Bearing Various C4'-Side Chains with a Late-Stage Diversification Method.

Gong X, Sun C, Abame MA, Shi W, Xie Y, Xu W, Zhu F, Zhang Y, Shen J, Aisa HA. Gong X, et al. J Org Chem. 2020 Feb 21;85(4):2704-2715. doi: 10.1021/acs.joc.9b02880. Epub 2020 Jan 8. J Org Chem. 2020. PMID: 31885270

8

Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir.

Yin W, Mao C, Luan X, Shen DD, Shen Q, Su H, Wang X, Zhou F, Zhao W, Gao M, Chang S, Xie YC, Tian G, Jiang HW, Tao SC, Shen J, Jiang Y, Jiang H, Xu Y, Zhang S, Zhang Y, Xu HE. Yin W, et al. Science. 2020 Jun 26;368(6498):1499-1504. doi: 10.1126/science.abc1560. Epub 2020 May 1. Science. 2020. PMID: 32358203 Free PMC article.

9

Species differences in the CYP3A-catalyzed metabolism of TPN729, a novel PDE5 inhibitor.

Tian QQ, Zhu YT, Diao XX, Zhang XL, Xu YC, Jiang XR, Shen JS, Wang Z, Zhong DF. Tian QQ, et al. Among authors: shen js. Acta Pharmacol Sin. 2021 Mar;42(3):482-490. doi: 10.1038/s41401-020-0447-x. Epub 2020 Jun 24. Acta Pharmacol Sin. 2021. PMID: 32581257 Free PMC article.

10

Automated design and optimization of multitarget schizophrenia drug candidates by deep learning.

Tan X, Jiang X, He Y, Zhong F, Li X, Xiong Z, Li Z, Liu X, Cui C, Zhao Q, Xie Y, Yang F, Wu C, Shen J, Zheng M, Wang Z, Jiang H. Tan X, et al. Eur J Med Chem. 2020 Oct 15;204:112572. doi: 10.1016/j.ejmech.2020.112572. Epub 2020 Jul 12. Eur J Med Chem. 2020. PMID: 32711293

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