Yin O - Search Results

1

Population Pharmacokinetic Analysis of Pexidartinib in Healthy Subjects and Patients With Tenosynovial Giant Cell Tumor or Other Solid Tumors.

Yin O, Wagner AJ, Kang J, Knebel W, Zahir H, van de Sande M, Tap WD, Gelderblom H, Healey JH, Shuster D, Stacchiotti S. Yin O, et al. J Clin Pharmacol. 2021 Apr;61(4):480-492. doi: 10.1002/jcph.1753. Epub 2020 Oct 11. J Clin Pharmacol. 2021. PMID: 33043474 Free PMC article. Clinical Trial.

2

Exposure-response analysis of efficacy and safety for pexidartinib in patients with tenosynovial giant cell tumor.

Yin O, Zahir H, French J, Polhamus D, Wang X, van de Sande M, Tap WD, Gelderblom H, Wagner AJ, Healey JH, Greenberg J, Shuster D, Stacchiotti S. Yin O, et al. CPT Pharmacometrics Syst Pharmacol. 2021 Nov;10(11):1422-1432. doi: 10.1002/psp4.12712. Epub 2021 Oct 14. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 34585528 Free PMC article.

3

Population Pharmacokinetic Analysis of Quizartinib in Healthy Volunteers and Patients With Relapsed/Refractory Acute Myeloid Leukemia.

Kang D, Ludwig E, Jaworowicz D, Huang H, Fiedler-Kelly J, Cortes J, Ganguly S, Khaled S, Krämer A, Levis M, Martinelli G, Perl A, Russell N, Abutarif M, Choi Y, Mendell J, Yin O. Kang D, et al. Among authors: yin o. J Clin Pharmacol. 2020 Dec;60(12):1629-1641. doi: 10.1002/jcph.1680. Epub 2020 Jun 29. J Clin Pharmacol. 2020. PMID: 32598495 Free PMC article.

4

Population Pharmacokinetics of Trastuzumab Deruxtecan in Patients With HER2-Positive Breast Cancer and Other Solid Tumors.

Yin O, Xiong Y, Endo S, Yoshihara K, Garimella T, AbuTarif M, Wada R, LaCreta F. Yin O, et al. Clin Pharmacol Ther. 2021 May;109(5):1314-1325. doi: 10.1002/cpt.2096. Epub 2020 Dec 6. Clin Pharmacol Ther. 2021. PMID: 33118153 Free PMC article.

5

First-in-Human Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of an Oral Formulation of DS-1040, an Inhibitor of the Activated Form of Thrombin-Activatable Fibrinolysis Inhibitor, in Healthy Subjects.

Zhou J, Limsakun T, Yin O, Warren V, Zamora C, Atiee G, Kochan J, Pav J, Kobayashi F, Vashi V, Dishy V. Zhou J, et al. Among authors: yin o. J Clin Pharmacol. 2019 Dec;59(12):1669-1677. doi: 10.1002/jcph.1474. Epub 2019 Jun 27. J Clin Pharmacol. 2019. PMID: 31243790 Clinical Trial.

6

Population pharmacokinetic modeling and simulation for assessing renal impairment effect on the pharmacokinetics of mirogabalin.

Yin OQ, Merante D, Truitt K, Miller R. Yin OQ, et al. J Clin Pharmacol. 2016 Feb;56(2):203-12. doi: 10.1002/jcph.584. Epub 2015 Sep 2. J Clin Pharmacol. 2016. PMID: 26138993 Clinical Trial.

7

Edoxaban population pharmacokinetics and exposure-response analysis in patients with non-valvular atrial fibrillation.

Yin OQ, Tetsuya K, Miller R. Yin OQ, et al. Eur J Clin Pharmacol. 2014 Nov;70(11):1339-51. doi: 10.1007/s00228-014-1736-4. Epub 2014 Aug 29. Eur J Clin Pharmacol. 2014. PMID: 25168620 Clinical Trial.

8

Exposure-Response Relationships in Patients With HER2-Positive Metastatic Breast Cancer and Other Solid Tumors Treated With Trastuzumab Deruxtecan.

Yin O, Iwata H, Lin CC, Tamura K, Watanabe J, Wada R, Kastrissios H, AbuTarif M, Garimella T, Lee C, Zhang L, Shahidi J, LaCreta F. Yin O, et al. Clin Pharmacol Ther. 2021 Oct;110(4):986-996. doi: 10.1002/cpt.2291. Epub 2021 Jun 10. Clin Pharmacol Ther. 2021. PMID: 33999422 Free PMC article.

9

Edoxaban Exposure in Patients With Atrial Fibrillation and Estimated Creatinine Clearance Exceeding 100 mL/min.

Yin O, Kakkar T, Duggal A, Kotsuma M, Shi M, Lanz H, Grosso MA. Yin O, et al. Clin Pharmacol Drug Dev. 2022 May;11(5):666-674. doi: 10.1002/cpdd.1050. Epub 2021 Dec 7. Clin Pharmacol Drug Dev. 2022. PMID: 34877813 Free PMC article. Clinical Trial.

10

Population pharmacokinetic and exposure-response analysis of nilotinib in patients with newly diagnosed Ph+ chronic myeloid leukemia in chronic phase.

Larson RA, Yin OQ, Hochhaus A, Saglio G, Clark RE, Nakamae H, Gallagher NJ, Demirhan E, Hughes TP, Kantarjian HM, le Coutre PD. Larson RA, et al. Eur J Clin Pharmacol. 2012 May;68(5):723-33. doi: 10.1007/s00228-011-1200-7. Epub 2011 Dec 30. Eur J Clin Pharmacol. 2012. PMID: 22207416 Free PMC article. Clinical Trial.

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