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Vesatolimod, a Toll-like Receptor 7 Agonist, Induces Immune Activation in Virally Suppressed Adults Living With Human Immunodeficiency Virus-1.
Riddler SA, Para M, Benson CA, Mills A, Ramgopal M, DeJesus E, Brinson C, Cyktor J, Jacobs J, Koontz D, Mellors JW, Laird GM, Wrin T, Patel H, Guo S, Wallin J, Boice J, Zhang L, Humeniuk R, Begley R, German P, Graham H, Geleziunas R, Brainard DM, SenGupta D. Riddler SA, et al. Among authors: zhang l. Clin Infect Dis. 2021 Jun 1;72(11):e815-e824. doi: 10.1093/cid/ciaa1534. Clin Infect Dis. 2021. PMID: 33043969 Clinical Trial.
The TLR7 agonist vesatolimod induced a modest delay in viral rebound in HIV controllers after cessation of antiretroviral therapy.
SenGupta D, Brinson C, DeJesus E, Mills A, Shalit P, Guo S, Cai Y, Wallin JJ, Zhang L, Humeniuk R, Begley R, Geleziunas R, Mellors J, Wrin T, Jones N, Milush J, Ferre AL, Shacklett BL, Laird GM, Moldt B, Vendrame E, Brainard DM, Ramgopal M, Deeks SG. SenGupta D, et al. Among authors: zhang l. Sci Transl Med. 2021 Jun 23;13(599):eabg3071. doi: 10.1126/scitranslmed.abg3071. Sci Transl Med. 2021. PMID: 34162752 Clinical Trial.
HIV rebound in HIV controllers is associated with a specific fecal microbiome profile.
Cai Y, Podlaha O, Deeks SG, Brinson C, Ramgopal MN, DeJesus E, Mills A, Shalit P, Abdel-Mohsen M, Zhang L, de Vries CR, Vendrame E, SenGupta D, Wallin JJ. Cai Y, et al. Among authors: zhang l. Eur J Immunol. 2024 Aug;54(8):e2350809. doi: 10.1002/eji.202350809. Epub 2024 May 10. Eur J Immunol. 2024. PMID: 38727191
Circulating immune and plasma biomarkers of time to HIV rebound in HIV controllers treated with vesatolimod.
Abdel-Mohsen M, Deeks S, Giron L, Hong KY, Goldman A, Zhang L, Huang SSY, Verrill D, Guo S, Selzer L, de Vries CR, Vendrame E, SenGupta D, Wallin JJ, Cai Y. Abdel-Mohsen M, et al. Among authors: zhang l. Front Immunol. 2024 Jun 24;15:1405348. doi: 10.3389/fimmu.2024.1405348. eCollection 2024. Front Immunol. 2024. PMID: 38979421 Free PMC article. Clinical Trial.
A Pooled Analysis of Eight Clinical Studies Suggests a Link Between Influenza-Like Symptoms and Pharmacodynamics of the Toll-Like Receptor-7 Agonist Vesatolimod.
Riddler SA, Benson CA, Brinson C, Deeks SG, DeJesus E, Mills A, Para MF, Ramgopal MN, Cai Y, Zheng Y, Zhang L, Jiang W, Liu X, Verrill D, Lim D, de Vries CR, Wallin JJ, Vendrame E, SenGupta D. Riddler SA, et al. Among authors: zhang l. Infect Dis Ther. 2024 Nov;13(11):2285-2299. doi: 10.1007/s40121-024-01034-w. Epub 2024 Sep 15. Infect Dis Ther. 2024. PMID: 39278975 Free PMC article.
[Potential of new self-crosslinked hyaluronic acid gel on the recovery of endometrium after artificial abortion: a multicenter, prospective randomized controlled trial].
Li CY, Teng LR, Lin Q, Zhao LP, Zhu YX, Mi X, Wang ZN, Wang XY, Zhang LS, Han D, Ma LL, Bai WP, Wang JM, Ni J, Shen HP, Chen QF, Xu HM, Ren CC, Jiang J, Liu GY, Peng P, Liu XY. Li CY, et al. Among authors: zhang ls. Zhonghua Fu Chan Ke Za Zhi. 2024 Nov 25;59(11):864-870. doi: 10.3760/cma.j.cn112141-20240906-00493. Zhonghua Fu Chan Ke Za Zhi. 2024. PMID: 39581771 Clinical Trial. Chinese.
Online registry of neonatal necrotising enterocolitis in Shenzhen: protocol for a multicentre, prospective, open, observational cohort study.
Guo X, Feng J, Zhao X, Ying E, Liu D, Tu H, Yan Y, Huang H, Li X, Chen X, Zeng S, Lin Y, Zhou K, Zhang L, Yuan S, Zhang Q, Lin F, Dou L, Chai Y, Cai Y, Liu R, Bai L, Chen T, Chen Z, Wang Z, Li Y, Gong X, Fang X, Zhang A, Li G, Liao Z, Chen C, Chen J, Guo Y, Liu Y, Tang H, Lin H, Rao DD. Guo X, et al. Among authors: zhang l. BMJ Open. 2024 Nov 24;14(11):e091290. doi: 10.1136/bmjopen-2024-091290. BMJ Open. 2024. PMID: 39581716
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