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Page 1
IL-27 signalling regulates glycolysis in Th1 cells to limit immunopathology during infection.
Montes de Oca M, de Labastida Rivera F, Winterford C, Frame TCM, Ng SS, Amante FH, Edwards CL, Bukali L, Wang Y, Uzonna JE, Kuns RD, Zhang P, Kabat A, Klein Geltink RI, Pearce EJ, Hill GR, Engwerda CR. Montes de Oca M, et al. Among authors: pearce ej. PLoS Pathog. 2020 Oct 13;16(10):e1008994. doi: 10.1371/journal.ppat.1008994. eCollection 2020 Oct. PLoS Pathog. 2020. PMID: 33049000 Free PMC article.
Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming.
Buck MD, O'Sullivan D, Klein Geltink RI, Curtis JD, Chang CH, Sanin DE, Qiu J, Kretz O, Braas D, van der Windt GJ, Chen Q, Huang SC, O'Neill CM, Edelson BT, Pearce EJ, Sesaki H, Huber TB, Rambold AS, Pearce EL. Buck MD, et al. Among authors: pearce ej, pearce el. Cell. 2016 Jun 30;166(1):63-76. doi: 10.1016/j.cell.2016.05.035. Epub 2016 Jun 9. Cell. 2016. PMID: 27293185 Free PMC article.
Inflammation by way of macrophage metabolism.
Kabat AM, Pearce EJ. Kabat AM, et al. Among authors: pearce ej. Science. 2017 May 5;356(6337):488-489. doi: 10.1126/science.aan2691. Science. 2017. PMID: 28473549 No abstract available.
Mitochondrial Membrane Potential Regulates Nuclear Gene Expression in Macrophages Exposed to Prostaglandin E2.
Sanin DE, Matsushita M, Klein Geltink RI, Grzes KM, van Teijlingen Bakker N, Corrado M, Kabat AM, Buck MD, Qiu J, Lawless SJ, Cameron AM, Villa M, Baixauli F, Patterson AE, Hässler F, Curtis JD, O'Neill CM, O'Sullivan D, Wu D, Mittler G, Huang SC, Pearce EL, Pearce EJ. Sanin DE, et al. Among authors: pearce ej, pearce el. Immunity. 2018 Dec 18;49(6):1021-1033.e6. doi: 10.1016/j.immuni.2018.10.011. Immunity. 2018. PMID: 30566880 Free PMC article.
Acetate Promotes T Cell Effector Function during Glucose Restriction.
Qiu J, Villa M, Sanin DE, Buck MD, O'Sullivan D, Ching R, Matsushita M, Grzes KM, Winkler F, Chang CH, Curtis JD, Kyle RL, Van Teijlingen Bakker N, Corrado M, Haessler F, Alfei F, Edwards-Hicks J, Maggi LB Jr, Zehn D, Egawa T, Bengsch B, Klein Geltink RI, Jenuwein T, Pearce EJ, Pearce EL. Qiu J, et al. Among authors: pearce ej, pearce el. Cell Rep. 2019 May 14;27(7):2063-2074.e5. doi: 10.1016/j.celrep.2019.04.022. Cell Rep. 2019. PMID: 31091446 Free PMC article.
Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation.
Puleston DJ, Buck MD, Klein Geltink RI, Kyle RL, Caputa G, O'Sullivan D, Cameron AM, Castoldi A, Musa Y, Kabat AM, Zhang Y, Flachsmann LJ, Field CS, Patterson AE, Scherer S, Alfei F, Baixauli F, Austin SK, Kelly B, Matsushita M, Curtis JD, Grzes KM, Villa M, Corrado M, Sanin DE, Qiu J, Pällman N, Paz K, Maccari ME, Blazar BR, Mittler G, Buescher JM, Zehn D, Rospert S, Pearce EJ, Balabanov S, Pearce EL. Puleston DJ, et al. Among authors: pearce ej, pearce el. Cell Metab. 2019 Aug 6;30(2):352-363.e8. doi: 10.1016/j.cmet.2019.05.003. Epub 2019 May 23. Cell Metab. 2019. PMID: 31130465 Free PMC article.
Metabolic conditioning of CD8+ effector T cells for adoptive cell therapy.
Klein Geltink RI, Edwards-Hicks J, Apostolova P, O'Sullivan D, Sanin DE, Patterson AE, Puleston DJ, Ligthart NAM, Buescher JM, Grzes KM, Kabat AM, Stanczak M, Curtis JD, Hässler F, Uhl FM, Fabri M, Zeiser R, Pearce EJ, Pearce EL. Klein Geltink RI, et al. Among authors: pearce ej, pearce el. Nat Metab. 2020 Aug;2(8):703-716. doi: 10.1038/s42255-020-0256-z. Epub 2020 Aug 3. Nat Metab. 2020. PMID: 32747793 Free PMC article.
Triacylglycerol synthesis enhances macrophage inflammatory function.
Castoldi A, Monteiro LB, van Teijlingen Bakker N, Sanin DE, Rana N, Corrado M, Cameron AM, Hässler F, Matsushita M, Caputa G, Klein Geltink RI, Büscher J, Edwards-Hicks J, Pearce EL, Pearce EJ. Castoldi A, et al. Among authors: pearce ej, pearce el. Nat Commun. 2020 Aug 14;11(1):4107. doi: 10.1038/s41467-020-17881-3. Nat Commun. 2020. PMID: 32796836 Free PMC article.
255 results