Krishnamurthy S - Search Results

1

Genome-wide screens identify Toxoplasma gondii determinants of parasite fitness in IFNγ-activated murine macrophages.

Wang Y, Sangaré LO, Paredes-Santos TC, Hassan MA, Krishnamurthy S, Furuta AM, Markus BM, Lourido S, Saeij JPJ. Wang Y, et al. Among authors: krishnamurthy s. Nat Commun. 2020 Oct 16;11(1):5258. doi: 10.1038/s41467-020-18991-8. Nat Commun. 2020. PMID: 33067458 Free PMC article.

2

The human immune response to Toxoplasma: Autophagy versus cell death.

Krishnamurthy S, Konstantinou EK, Young LH, Gold DA, Saeij JP. Krishnamurthy S, et al. PLoS Pathog. 2017 Mar 9;13(3):e1006176. doi: 10.1371/journal.ppat.1006176. eCollection 2017 Mar. PLoS Pathog. 2017. PMID: 28278184 Free PMC article. Review. No abstract available.

3

Toxoplasma Does Not Secrete the GRA16 and GRA24 Effectors Beyond the Parasitophorous Vacuole Membrane of Tissue Cysts.

Krishnamurthy S, Saeij JPJ. Krishnamurthy S, et al. Front Cell Infect Microbiol. 2018 Oct 18;8:366. doi: 10.3389/fcimb.2018.00366. eCollection 2018. Front Cell Infect Microbiol. 2018. PMID: 30406043 Free PMC article.

4

CRISPR Screens Identify Toxoplasma Genes That Determine Parasite Fitness in Interferon Gamma-Stimulated Human Cells.

Krishnamurthy S, Maru P, Wang Y, Bitew MA, Mukhopadhyay D, Yamaryo-Botté Y, Paredes-Santos TC, Sangaré LO, Swale C, Botté CY, Saeij JPJ. Krishnamurthy S, et al. mBio. 2023 Apr 25;14(2):e0006023. doi: 10.1128/mbio.00060-23. Epub 2023 Mar 14. mBio. 2023. PMID: 36916910 Free PMC article.

5

Genome-wide CRISPR screen identifies genes synthetically lethal with GRA17, a nutrient channel encoding gene in Toxoplasma.

Paredes-Santos TC, Bitew MA, Swale C, Rodriguez F, Krishnamurthy S, Wang Y, Maru P, Sangaré LO, Saeij JPJ. Paredes-Santos TC, et al. Among authors: krishnamurthy s. PLoS Pathog. 2023 Jul 27;19(7):e1011543. doi: 10.1371/journal.ppat.1011543. eCollection 2023 Jul. PLoS Pathog. 2023. PMID: 37498952 Free PMC article.

6

Host E3 ubiquitin ligase ITCH mediates Toxoplasma gondii effector GRA35-triggered NLRP1 inflammasome activation and cell-autonomous immunity.

Wang Y, Hollingsworth LR, Sangaré LO, Paredes-Santos TC, Krishnamurthy S, Penn BH, Wu H, Saeij JPJ. Wang Y, et al. Among authors: krishnamurthy s. bioRxiv [Preprint]. 2023 Dec 14:2023.12.13.571530. doi: 10.1101/2023.12.13.571530. bioRxiv. 2023. Update in: mBio. 2024 Mar 13;15(3):e0330223. doi: 10.1128/mbio.03302-23 PMID: 38168400 Free PMC article. Updated. Preprint.

7

Host E3 ubiquitin ligase ITCH mediates Toxoplasma gondii effector GRA35-triggered NLRP1 inflammasome activation and cell-autonomous immunity.

Wang Y, Hollingsworth LR, Sangaré LO, Paredes-Santos TC, Krishnamurthy S, Penn BH, Wu H, Saeij JPJ. Wang Y, et al. Among authors: krishnamurthy s. mBio. 2024 Mar 13;15(3):e0330223. doi: 10.1128/mbio.03302-23. Epub 2024 Feb 20. mBio. 2024. PMID: 38376248 Free PMC article.

8

Global Analysis of Palmitoylated Proteins in Toxoplasma gondii.

Foe IT, Child MA, Majmudar JD, Krishnamurthy S, van der Linden WA, Ward GE, Martin BR, Bogyo M. Foe IT, et al. Among authors: krishnamurthy s. Cell Host Microbe. 2015 Oct 14;18(4):501-11. doi: 10.1016/j.chom.2015.09.006. Cell Host Microbe. 2015. PMID: 26468752 Free PMC article.

9

Not a Simple Tether: Binding of Toxoplasma gondii AMA1 to RON2 during Invasion Protects AMA1 from Rhomboid-Mediated Cleavage and Leads to Dephosphorylation of Its Cytosolic Tail.

Krishnamurthy S, Deng B, Del Rio R, Buchholz KR, Treeck M, Urban S, Boothroyd J, Lam YW, Ward GE. Krishnamurthy S, et al. mBio. 2016 Sep 13;7(5):e00754-16. doi: 10.1128/mBio.00754-16. mBio. 2016. PMID: 27624124 Free PMC article.

10

Identification of TgCBAP, a novel cytoskeletal protein that localizes to three distinct subcompartments of the Toxoplasma gondii pellicle.

Tilley LD, Krishnamurthy S, Westwood NJ, Ward GE. Tilley LD, et al. Among authors: krishnamurthy s. PLoS One. 2014 Jun 2;9(6):e98492. doi: 10.1371/journal.pone.0098492. eCollection 2014. PLoS One. 2014. PMID: 24887026 Free PMC article.

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