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Guanosine triphosphate links MYC-dependent metabolic and ribosome programs in small-cell lung cancer.
Huang F, Huffman KE, Wang Z, Wang X, Li K, Cai F, Yang C, Cai L, Shih TS, Zacharias LG, Chung A, Yang Q, Chalishazar MD, Ireland AS, Stewart CA, Cargill K, Girard L, Liu Y, Ni M, Xu J, Wu X, Zhu H, Drapkin B, Byers LA, Oliver TG, Gazdar AF, Minna JD, DeBerardinis RJ. Huang F, et al. Among authors: drapkin b. J Clin Invest. 2021 Jan 4;131(1):e139929. doi: 10.1172/JCI139929. J Clin Invest. 2021. PMID: 33079728 Free PMC article.
Studying Lineage Plasticity One Cell at a Time.
Drapkin BJ, Minna JD. Drapkin BJ, et al. Cancer Cell. 2020 Aug 10;38(2):150-152. doi: 10.1016/j.ccell.2020.07.001. Cancer Cell. 2020. PMID: 32781039 Free article.
Cell-autonomous immune gene expression is repressed in pulmonary neuroendocrine cells and small cell lung cancer.
Cai L, Liu H, Huang F, Fujimoto J, Girard L, Chen J, Li Y, Zhang YA, Deb D, Stastny V, Pozo K, Kuo CS, Jia G, Yang C, Zou W, Alomar A, Huffman K, Papari-Zareei M, Yang L, Drapkin B, Akbay EA, Shames DS, Wistuba II, Wang T, Johnson JE, Xiao G, DeBerardinis RJ, Minna JD, Xie Y, Gazdar AF. Cai L, et al. Among authors: drapkin b. Commun Biol. 2021 Mar 9;4(1):314. doi: 10.1038/s42003-021-01842-7. Commun Biol. 2021. PMID: 33750914 Free PMC article.
How lung cancer cells change identity.
von Itzstein MS, Drapkin BJ, Minna JD. von Itzstein MS, et al. Elife. 2021 Aug 4;10:e71610. doi: 10.7554/eLife.71610. Elife. 2021. PMID: 34346867 Free PMC article.
Unfolding the secrets of small cell lung cancer progression: Novel approaches and insights through rapid autopsies.
Megyesfalvi Z, Heeke S, Drapkin BJ, Solta A, Kovacs I, Boettiger K, Horvath L, Ernhofer B, Fillinger J, Renyi-Vamos F, Aigner C, Schelch K, Lang C, Marko-Varga G, Gay CM, Byers LA, Morris BB, Heymach JV, Van Loo P, Hirsch FR, Dome B. Megyesfalvi Z, et al. Among authors: drapkin bj. Cancer Cell. 2023 Sep 11;41(9):1535-1540. doi: 10.1016/j.ccell.2023.08.007. Cancer Cell. 2023. PMID: 37699331 Free PMC article.
Induced degradation of lineage-specific oncoproteins drives the therapeutic vulnerability of small cell lung cancer to PARP inhibitors.
Kim C, Wang XD, Liu Z, Hao J, Wang S, Li P, Zi Z, Ding Q, Jang S, Kim J, Luo Y, Huffman KE, Pal Choudhuri S, Del Rio S, Cai L, Liang H, Drapkin BJ, Minna JD, Yu Y. Kim C, et al. Among authors: drapkin bj. Sci Adv. 2024 Jan 19;10(3):eadh2579. doi: 10.1126/sciadv.adh2579. Epub 2024 Jan 19. Sci Adv. 2024. PMID: 38241363 Free PMC article.
Acquired Cross-Resistance in Small Cell Lung Cancer due to Extrachromosomal DNA Amplification of MYC Paralogs.
Pal Choudhuri S, Girard L, Lim JYS, Wise JF, Freitas B, Yang D, Wong E, Hamilton S, Chien VD, Kim YJ, Gilbreath C, Zhong J, Phat S, Myers DT, Christensen CL, Mazloom-Farsibaf H, Stanzione M, Wong KK, Hung YP, Farago AF, Meador CB, Dyson NJ, Lawrence MS, Wu S, Drapkin BJ. Pal Choudhuri S, et al. Among authors: drapkin bj. Cancer Discov. 2024 May 1;14(5):804-827. doi: 10.1158/2159-8290.CD-23-0656. Cancer Discov. 2024. PMID: 38386926 Free PMC article.
Identification of DHODH as a therapeutic target in small cell lung cancer.
Li L, Ng SR, Colón CI, Drapkin BJ, Hsu PP, Li Z, Nabel CS, Lewis CA, Romero R, Mercer KL, Bhutkar A, Phat S, Myers DT, Muzumdar MD, Westcott PMK, Beytagh MC, Farago AF, Vander Heiden MG, Dyson NJ, Jacks T. Li L, et al. Sci Transl Med. 2019 Nov 6;11(517):eaaw7852. doi: 10.1126/scitranslmed.aaw7852. Sci Transl Med. 2019. PMID: 31694929 Free PMC article.
38 results