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Design and synthesis of novel pyrazolo[3,4-d]pyrimidin-4-one bearing quinoline scaffold as potent dual PDE5 inhibitors and apoptotic inducers for cancer therapy.
Ibrahim TS, Hawwas MM, Taher ES, Alhakamy NA, Alfaleh MA, Elagawany M, Elgendy B, Zayed GM, Mohamed MFA, Abdel-Samii ZK, Elshaier YAMM. Ibrahim TS, et al. Among authors: elgendy b. Bioorg Chem. 2020 Dec;105:104352. doi: 10.1016/j.bioorg.2020.104352. Epub 2020 Oct 8. Bioorg Chem. 2020. PMID: 33080494
Ligand-based design, synthesis, computational insights, and in vitro studies of novel N-(5-Nitrothiazol-2-yl)-carboxamido derivatives as potent inhibitors of SARS-CoV-2 main protease.
Elagawany M, Elmaaty AA, Mostafa A, Abo Shama NM, Santali EY, Elgendy B, Al-Karmalawy AA. Elagawany M, et al. Among authors: elgendy b. J Enzyme Inhib Med Chem. 2022 Dec;37(1):2112-2132. doi: 10.1080/14756366.2022.2105322. J Enzyme Inhib Med Chem. 2022. PMID: 35912578 Free PMC article.
48 results