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Design and synthesis of novel pyrazolo[3,4-d]pyrimidin-4-one bearing quinoline scaffold as potent dual PDE5 inhibitors and apoptotic inducers for cancer therapy.
Ibrahim TS, Hawwas MM, Taher ES, Alhakamy NA, Alfaleh MA, Elagawany M, Elgendy B, Zayed GM, Mohamed MFA, Abdel-Samii ZK, Elshaier YAMM. Ibrahim TS, et al. Among authors: taher es. Bioorg Chem. 2020 Dec;105:104352. doi: 10.1016/j.bioorg.2020.104352. Epub 2020 Oct 8. Bioorg Chem. 2020. PMID: 33080494
Design, synthesis and biological evaluation of novel 5-((substituted quinolin-3-yl/1-naphthyl) methylene)-3-substituted imidazolidin-2,4-dione as HIV-1 fusion inhibitors.
Ibrahim TS, Bokhtia RM, Al-Mahmoudy AMM, Taher ES, AlAwadh MA, Elagawany M, Abdel-Aal EH, Panda S, Gouda AM, Asfour HZ, Alhakamy NA, Youssif BGM. Ibrahim TS, et al. Among authors: taher es. Bioorg Chem. 2020 Jun;99:103782. doi: 10.1016/j.bioorg.2020.103782. Epub 2020 Mar 24. Bioorg Chem. 2020. PMID: 32229348
In Vitro Antimycobacterial Activity and Physicochemical Characterization of Diaryl Ether Triclosan Analogues as Potential InhA Reductase Inhibitors.
Ibrahim TS, Taher ES, Samir E, M Malebari A, Khayyat AN, Mohamed MFA, Bokhtia RM, AlAwadh MA, Seliem IA, Asfour HZ, Alhakamy NA, Panda SS, Al-Mahmoudy AMM. Ibrahim TS, et al. Among authors: taher es. Molecules. 2020 Jul 8;25(14):3125. doi: 10.3390/molecules25143125. Molecules. 2020. PMID: 32650556 Free PMC article.
Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect.
Ibrahim TS, Hawwas MM, Malebari AM, Taher ES, Omar AM, Neamatallah T, Abdel-Samii ZK, Safo MK, Elshaier YAMM. Ibrahim TS, et al. Among authors: taher es. J Enzyme Inhib Med Chem. 2021 Dec;36(1):802-818. doi: 10.1080/14756366.2021.1899168. J Enzyme Inhib Med Chem. 2021. PMID: 33730937 Free PMC article.
Design, synthesis, biological evaluation, and computational studies of novel thiazolo-pyrazole hybrids as promising selective COX-2 inhibitors: Implementation of apoptotic genes expression for ulcerogenic liability assessment.
Marzouk AA, Taher ES, Shaykoon MSA, Lan P, Abd-Allah WH, Aboregela AM, El-Behairy MF. Marzouk AA, et al. Among authors: taher es. Bioorg Chem. 2021 Jun;111:104883. doi: 10.1016/j.bioorg.2021.104883. Epub 2021 Mar 31. Bioorg Chem. 2021. PMID: 33865053
49 results