Schreiber A - Search Results

1

Semisynthetic Cardenolides Acting as Antiviral Inhibitors of Influenza A Virus Replication by Preventing Polymerase Complex Formation.

Boff L, Schreiber A, da Rocha Matos A, Del Sarto J, Brunotte L, Munkert J, Melo Ottoni F, Silva Ramos G, Kreis W, Castro Braga F, José Alves R, Maia de Pádua R, Maria Oliveira Simões C, Ludwig S. Boff L, et al. Among authors: schreiber a. Molecules. 2020 Oct 21;25(20):4853. doi: 10.3390/molecules25204853. Molecules. 2020. PMID: 33096707 Free PMC article.

2

The MEK-inhibitor CI-1040 displays a broad anti-influenza virus activity in vitro and provides a prolonged treatment window compared to standard of care in vivo.

Haasbach E, Müller C, Ehrhardt C, Schreiber A, Pleschka S, Ludwig S, Planz O. Haasbach E, et al. Among authors: schreiber a. Antiviral Res. 2017 Jun;142:178-184. doi: 10.1016/j.antiviral.2017.03.024. Epub 2017 Apr 2. Antiviral Res. 2017. PMID: 28377100 Free article.

3

The clinically approved MEK inhibitor Trametinib efficiently blocks influenza A virus propagation and cytokine expression.

Schräder T, Dudek SE, Schreiber A, Ehrhardt C, Planz O, Ludwig S. Schräder T, et al. Among authors: schreiber a. Antiviral Res. 2018 Sep;157:80-92. doi: 10.1016/j.antiviral.2018.07.006. Epub 2018 Jul 7. Antiviral Res. 2018. PMID: 29990517 Free article.

4

Type I interferon antagonistic properties of influenza B virus polymerase proteins.

Schreiber A, Liedmann S, Brunotte L, Anhlan D, Ehrhardt C, Ludwig S. Schreiber A, et al. Cell Microbiol. 2020 Feb;22(2):e13143. doi: 10.1111/cmi.13143. Epub 2019 Dec 8. Cell Microbiol. 2020. PMID: 31711273

5

Antiviral efficacy against influenza virus and pharmacokinetic analysis of a novel MEK-inhibitor, ATR-002, in cell culture and in the mouse model.

Laure M, Hamza H, Koch-Heier J, Quernheim M, Müller C, Schreiber A, Müller G, Pleschka S, Ludwig S, Planz O. Laure M, et al. Among authors: schreiber a. Antiviral Res. 2020 Jun;178:104806. doi: 10.1016/j.antiviral.2020.104806. Epub 2020 Apr 15. Antiviral Res. 2020. PMID: 32304723 Free article.

6

Dissecting the mechanism of signaling-triggered nuclear export of newly synthesized influenza virus ribonucleoprotein complexes.

Schreiber A, Boff L, Anhlan D, Krischuns T, Brunotte L, Schuberth C, Wedlich-Söldner R, Drexler H, Ludwig S. Schreiber A, et al. Proc Natl Acad Sci U S A. 2020 Jul 14;117(28):16557-16566. doi: 10.1073/pnas.2002828117. Epub 2020 Jun 29. Proc Natl Acad Sci U S A. 2020. PMID: 32601201 Free PMC article.

7

Discrete spatio-temporal regulation of tyrosine phosphorylation directs influenza A virus M1 protein towards its function in virion assembly.

Mecate-Zambrano A, Sukumar S, Seebohm G, Ciminski K, Schreiber A, Anhlan D, Greune L, Wixler L, Grothe S, Stein NC, Schmidt MA, Langer K, Schwemmle M, Shi T, Ludwig S, Boergeling Y. Mecate-Zambrano A, et al. Among authors: schreiber a. PLoS Pathog. 2020 Aug 31;16(8):e1008775. doi: 10.1371/journal.ppat.1008775. eCollection 2020 Aug. PLoS Pathog. 2020. PMID: 32866218 Free PMC article.

8

The Effector Domain of the Influenza A Virus Nonstructural Protein NS1 Triggers Host Shutoff by Mediating Inhibition and Global Deregulation of Host Transcription When Associated with Specific Structures in the Nucleus.

Nacken W, Schreiber A, Masemann D, Ludwig S. Nacken W, et al. Among authors: schreiber a. mBio. 2021 Oct 26;12(5):e0219621. doi: 10.1128/mBio.02196-21. Epub 2021 Sep 7. mBio. 2021. PMID: 34488451 Free PMC article.

9

The MEK1/2-inhibitor ATR-002 efficiently blocks SARS-CoV-2 propagation and alleviates pro-inflammatory cytokine/chemokine responses.

Schreiber A, Viemann D, Schöning J, Schloer S, Mecate Zambrano A, Brunotte L, Faist A, Schöfbänker M, Hrincius E, Hoffmann H, Hoffmann M, Pöhlmann S, Rescher U, Planz O, Ludwig S. Schreiber A, et al. Cell Mol Life Sci. 2022 Jan 10;79(1):65. doi: 10.1007/s00018-021-04085-1. Cell Mol Life Sci. 2022. PMID: 35013790 Free PMC article.

10

SARS-CoV-2 infects and replicates in photoreceptor and retinal ganglion cells of human retinal organoids.

Menuchin-Lasowski Y, Schreiber A, Lecanda A, Mecate-Zambrano A, Brunotte L, Psathaki OE, Ludwig S, Rauen T, Schöler HR. Menuchin-Lasowski Y, et al. Among authors: schreiber a. Stem Cell Reports. 2022 Apr 12;17(4):789-803. doi: 10.1016/j.stemcr.2022.02.015. Epub 2022 Mar 24. Stem Cell Reports. 2022. PMID: 35334213 Free PMC article.

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