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Bioinformatic analysis of RHO family of GTPases identifies RAC1 pharmacological inhibition as a new therapeutic strategy for hepatocellular carcinoma.
Bayo J, Fiore EJ, Dominguez LM, Cantero MJ, Ciarlantini MS, Malvicini M, Atorrasagasti C, Garcia MG, Rossi M, Cavasotto C, Martinez E, Comin J, Mazzolini GD. Bayo J, et al. Among authors: dominguez lm. Gut. 2021 Jul;70(7):1362-1374. doi: 10.1136/gutjnl-2020-321454. Epub 2020 Oct 26. Gut. 2021. PMID: 33106353
IMT504 blocks allodynia in rats with spared nerve injury by promoting the migration of mesenchymal stem cells and by favoring an anti-inflammatory milieu at the injured nerve.
Casadei M, Fiore E, Rubione J, Domínguez LM, Coronel MF, Leiguarda C, García M, Mazzolini G, Villar MJ, Montaner A, Constandil L, Romero-Sandoval EA, Brumovsky PR. Casadei M, et al. Among authors: dominguez lm. Pain. 2022 Jun 1;163(6):1114-1129. doi: 10.1097/j.pain.0000000000002476. Epub 2021 Sep 15. Pain. 2022. PMID: 34711765 Free PMC article.
36 results