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Page 1
Challenges and opportunities for improving the landscape for Lewy body dementia clinical trials.
Goldman JG, Forsberg LK, Boeve BF, Armstrong MJ, Irwin DJ, Ferman TJ, Galasko D, Galvin JE, Kaufer D, Leverenz J, Lippa CF, Marder K, Abler V, Biglan K, Irizarry M, Keller B, Munsie L, Nakagawa M, Taylor A, Graham T. Goldman JG, et al. Among authors: leverenz j. Alzheimers Res Ther. 2020 Oct 29;12(1):137. doi: 10.1186/s13195-020-00703-5. Alzheimers Res Ther. 2020. PMID: 33121510 Free PMC article. Review.
Rate of progression differs in frontotemporal dementia and Alzheimer disease.
Rascovsky K, Salmon DP, Lipton AM, Leverenz JB, DeCarli C, Jagust WJ, Clark CM, Mendez MF, Tang-Wai DF, Graff-Radford NR, Galasko D. Rascovsky K, et al. Among authors: leverenz jb. Neurology. 2005 Aug 9;65(3):397-403. doi: 10.1212/01.wnl.0000171343.43314.6e. Neurology. 2005. PMID: 16087904
DLB and PDD boundary issues: diagnosis, treatment, molecular pathology, and biomarkers.
Lippa CF, Duda JE, Grossman M, Hurtig HI, Aarsland D, Boeve BF, Brooks DJ, Dickson DW, Dubois B, Emre M, Fahn S, Farmer JM, Galasko D, Galvin JE, Goetz CG, Growdon JH, Gwinn-Hardy KA, Hardy J, Heutink P, Iwatsubo T, Kosaka K, Lee VM, Leverenz JB, Masliah E, McKeith IG, Nussbaum RL, Olanow CW, Ravina BM, Singleton AB, Tanner CM, Trojanowski JQ, Wszolek ZK; DLB/PDD Working Group. Lippa CF, et al. Among authors: leverenz jb. Neurology. 2007 Mar 13;68(11):812-9. doi: 10.1212/01.wnl.0000256715.13907.d3. Neurology. 2007. PMID: 17353469 Review.
GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology.
Tsuang D, Leverenz JB, Lopez OL, Hamilton RL, Bennett DA, Schneider JA, Buchman AS, Larson EB, Crane PK, Kaye JA, Kramer P, Woltjer R, Kukull W, Nelson PT, Jicha GA, Neltner JH, Galasko D, Masliah E, Trojanowski JQ, Schellenberg GD, Yearout D, Huston H, Fritts-Penniman A, Mata IF, Wan JY, Edwards KL, Montine TJ, Zabetian CP. Tsuang D, et al. Among authors: leverenz jb. Neurology. 2012 Nov 6;79(19):1944-50. doi: 10.1212/WNL.0b013e3182735e9a. Epub 2012 Oct 3. Neurology. 2012. PMID: 23035075 Free PMC article.
Neuropathologic substrates of Parkinson disease dementia.
Irwin DJ, White MT, Toledo JB, Xie SX, Robinson JL, Van Deerlin V, Lee VM, Leverenz JB, Montine TJ, Duda JE, Hurtig HI, Trojanowski JQ. Irwin DJ, et al. Among authors: leverenz jb. Ann Neurol. 2012 Oct;72(4):587-98. doi: 10.1002/ana.23659. Epub 2012 Oct 4. Ann Neurol. 2012. PMID: 23037886 Free PMC article.
APOE ε4 increases risk for dementia in pure synucleinopathies.
Tsuang D, Leverenz JB, Lopez OL, Hamilton RL, Bennett DA, Schneider JA, Buchman AS, Larson EB, Crane PK, Kaye JA, Kramer P, Woltjer R, Trojanowski JQ, Weintraub D, Chen-Plotkin AS, Irwin DJ, Rick J, Schellenberg GD, Watson GS, Kukull W, Nelson PT, Jicha GA, Neltner JH, Galasko D, Masliah E, Quinn JF, Chung KA, Yearout D, Mata IF, Wan JY, Edwards KL, Montine TJ, Zabetian CP. Tsuang D, et al. Among authors: leverenz jb. JAMA Neurol. 2013 Feb;70(2):223-8. doi: 10.1001/jamaneurol.2013.600. JAMA Neurol. 2013. PMID: 23407718 Free PMC article.
Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease.
Salloway S, Sperling R, Fox NC, Blennow K, Klunk W, Raskind M, Sabbagh M, Honig LS, Porsteinsson AP, Ferris S, Reichert M, Ketter N, Nejadnik B, Guenzler V, Miloslavsky M, Wang D, Lu Y, Lull J, Tudor IC, Liu E, Grundman M, Yuen E, Black R, Brashear HR; Bapineuzumab 301 and 302 Clinical Trial Investigators. Salloway S, et al. N Engl J Med. 2014 Jan 23;370(4):322-33. doi: 10.1056/NEJMoa1304839. N Engl J Med. 2014. PMID: 24450891 Free PMC article. Clinical Trial.
Arguing against the proposed definition changes of PD.
Boeve BF, Dickson DW, Duda JE, Ferman TJ, Galasko DR, Galvin JE, Goldman JG, Growdon JH, Hurtig HI, Kaufer DI, Kantarci K, Leverenz JB, Lippa CF, Lopez OL, McKeith IG, Singleton AB, Taylor A, Tsuang D, Weintraub D, Zabetian CP. Boeve BF, et al. Among authors: leverenz jb. Mov Disord. 2016 Nov;31(11):1619-1622. doi: 10.1002/mds.26721. Epub 2016 Aug 5. Mov Disord. 2016. PMID: 27492190 Free PMC article.
325 results