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Novel Aza-podophyllotoxin derivative induces oxidative phosphorylation and cell death via AMPK activation in triple-negative breast cancer.
Tailor D, Going CC, Resendez A, Kumar V, Nambiar DK, Li Y, Dheeraj A, LaGory EL, Ghoochani A, Birk AM, Stoyanova T, Ye J, Giaccia AJ, Le QT, Singh RP, Sledge GW, Pitteri SJ, Malhotra SV. Tailor D, et al. Among authors: ye j. Br J Cancer. 2021 Feb;124(3):604-615. doi: 10.1038/s41416-020-01137-4. Epub 2020 Nov 3. Br J Cancer. 2021. PMID: 33139797 Free PMC article.
p53 Suppresses Metabolic Stress-Induced Ferroptosis in Cancer Cells.
Tarangelo A, Magtanong L, Bieging-Rolett KT, Li Y, Ye J, Attardi LD, Dixon SJ. Tarangelo A, et al. Among authors: ye j. Cell Rep. 2018 Jan 16;22(3):569-575. doi: 10.1016/j.celrep.2017.12.077. Cell Rep. 2018. PMID: 29346757 Free PMC article.
Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism.
Li AM, Ducker GS, Li Y, Seoane JA, Xiao Y, Melemenidis S, Zhou Y, Liu L, Vanharanta S, Graves EE, Rankin EB, Curtis C, Massagué J, Rabinowitz JD, Thompson CB, Ye J. Li AM, et al. Among authors: ye j. Mol Cancer Res. 2020 Apr;18(4):599-611. doi: 10.1158/1541-7786.MCR-19-0606. Epub 2020 Jan 15. Mol Cancer Res. 2020. PMID: 31941752 Free PMC article.
The m6A RNA demethylase FTO is a HIF-independent synthetic lethal partner with the VHL tumor suppressor.
Xiao Y, Thakkar KN, Zhao H, Broughton J, Li Y, Seoane JA, Diep AN, Metzner TJ, von Eyben R, Dill DL, Brooks JD, Curtis C, Leppert JT, Ye J, Peehl DM, Giaccia AJ, Sinha S, Rankin EB. Xiao Y, et al. Among authors: ye j. Proc Natl Acad Sci U S A. 2020 Sep 1;117(35):21441-21449. doi: 10.1073/pnas.2000516117. Epub 2020 Aug 19. Proc Natl Acad Sci U S A. 2020. PMID: 32817424 Free PMC article.
Aldehyde dehydrogenase 3A1 deficiency leads to mitochondrial dysfunction and impacts salivary gland stem cell phenotype.
Viswanathan V, Cao H, Saiki J, Jiang D, Mattingly A, Nambiar D, Bloomstein J, Li Y, Jiang S, Chamoli M, Sirjani D, Kaplan M, Holsinger FC, Liang R, Von Eyben R, Jiang H, Guan L, Lagory E, Feng Z, Nolan G, Ye J, Denko N, Knox S, Rosen DM, Le QT. Viswanathan V, et al. Among authors: ye j. PNAS Nexus. 2022 Jun 9;1(2):pgac056. doi: 10.1093/pnasnexus/pgac056. eCollection 2022 May. PNAS Nexus. 2022. PMID: 35707206 Free PMC article.
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