Riddle DM - Search Results

1

Conformation-selective tau monoclonal antibodies inhibit tau pathology in primary neurons and a mouse model of Alzheimer's disease.

Gibbons GS, Kim SJ, Wu Q, Riddle DM, Leight SN, Changolkar L, Xu H, Meymand ES, O'Reilly M, Zhang B, Brunden KR, Trojanowski JQ, Lee VMY. Gibbons GS, et al. Among authors: riddle dm. Mol Neurodegener. 2020 Nov 4;15(1):64. doi: 10.1186/s13024-020-00404-5. Mol Neurodegener. 2020. PMID: 33148293 Free PMC article.

2

Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death.

Volpicelli-Daley LA, Luk KC, Patel TP, Tanik SA, Riddle DM, Stieber A, Meaney DF, Trojanowski JQ, Lee VM. Volpicelli-Daley LA, et al. Among authors: riddle dm. Neuron. 2011 Oct 6;72(1):57-71. doi: 10.1016/j.neuron.2011.08.033. Neuron. 2011. PMID: 21982369 Free PMC article.

3

Distinct α-synuclein strains differentially promote tau inclusions in neurons.

Guo JL, Covell DJ, Daniels JP, Iba M, Stieber A, Zhang B, Riddle DM, Kwong LK, Xu Y, Trojanowski JQ, Lee VM. Guo JL, et al. Among authors: riddle dm. Cell. 2013 Jul 3;154(1):103-17. doi: 10.1016/j.cell.2013.05.057. Cell. 2013. PMID: 23827677 Free PMC article.

4

Novel monoclonal antibodies to normal and pathologically altered human TDP-43 proteins.

Kwong LK, Irwin DJ, Walker AK, Xu Y, Riddle DM, Trojanowski JQ, Lee VM. Kwong LK, et al. Among authors: riddle dm. Acta Neuropathol Commun. 2014 Mar 31;2:33. doi: 10.1186/2051-5960-2-33. Acta Neuropathol Commun. 2014. PMID: 24690345 Free PMC article.

5

Formation of α-synuclein Lewy neurite-like aggregates in axons impedes the transport of distinct endosomes.

Volpicelli-Daley LA, Gamble KL, Schultheiss CE, Riddle DM, West AB, Lee VM. Volpicelli-Daley LA, et al. Among authors: riddle dm. Mol Biol Cell. 2014 Dec 15;25(25):4010-23. doi: 10.1091/mbc.E14-02-0741. Epub 2014 Oct 8. Mol Biol Cell. 2014. PMID: 25298402 Free PMC article.

6

Novel conformation-selective alpha-synuclein antibodies raised against different in vitro fibril forms show distinct patterns of Lewy pathology in Parkinson's disease.

Covell DJ, Robinson JL, Akhtar RS, Grossman M, Weintraub D, Bucklin HM, Pitkin RM, Riddle D, Yousef A, Trojanowski JQ, Lee VM. Covell DJ, et al. Neuropathol Appl Neurobiol. 2017 Dec;43(7):604-620. doi: 10.1111/nan.12402. Epub 2017 May 15. Neuropathol Appl Neurobiol. 2017. PMID: 28386933 Free PMC article.

7

Unbiased Proteomics of Early Lewy Body Formation Model Implicates Active Microtubule Affinity-Regulating Kinases (MARKs) in Synucleinopathies.

Henderson MX, Chung CH, Riddle DM, Zhang B, Gathagan RJ, Seeholzer SH, Trojanowski JQ, Lee VMY. Henderson MX, et al. Among authors: riddle dm. J Neurosci. 2017 Jun 14;37(24):5870-5884. doi: 10.1523/JNEUROSCI.2705-16.2017. Epub 2017 May 18. J Neurosci. 2017. PMID: 28522732 Free PMC article.

8

GFP-Mutant Human Tau Transgenic Mice Develop Tauopathy Following CNS Injections of Alzheimer's Brain-Derived Pathological Tau or Synthetic Mutant Human Tau Fibrils.

Gibbons GS, Banks RA, Kim B, Xu H, Changolkar L, Leight SN, Riddle DM, Li C, Gathagan RJ, Brown HJ, Zhang B, Trojanowski JQ, Lee VM. Gibbons GS, et al. Among authors: riddle dm. J Neurosci. 2017 Nov 22;37(47):11485-11494. doi: 10.1523/JNEUROSCI.2393-17.2017. Epub 2017 Oct 6. J Neurosci. 2017. PMID: 28986461 Free PMC article.

9

Detection of Alzheimer Disease (AD)-Specific Tau Pathology in AD and NonAD Tauopathies by Immunohistochemistry With Novel Conformation-Selective Tau Antibodies.

Gibbons GS, Banks RA, Kim B, Changolkar L, Riddle DM, Leight SN, Irwin DJ, Trojanowski JQ, Lee VMY. Gibbons GS, et al. Among authors: riddle dm. J Neuropathol Exp Neurol. 2018 Mar 1;77(3):216-228. doi: 10.1093/jnen/nly010. J Neuropathol Exp Neurol. 2018. PMID: 29415231 Free PMC article.

10

Differential α-synuclein expression contributes to selective vulnerability of hippocampal neuron subpopulations to fibril-induced toxicity.

Luna E, Decker SC, Riddle DM, Caputo A, Zhang B, Cole T, Caswell C, Xie SX, Lee VMY, Luk KC. Luna E, et al. Among authors: riddle dm. Acta Neuropathol. 2018 Jun;135(6):855-875. doi: 10.1007/s00401-018-1829-8. Epub 2018 Mar 3. Acta Neuropathol. 2018. PMID: 29502200 Free PMC article.

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