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Gut-educated IgA plasma cells defend the meningeal venous sinuses.
Fitzpatrick Z, Frazer G, Ferro A, Clare S, Bouladoux N, Ferdinand J, Tuong ZK, Negro-Demontel ML, Kumar N, Suchanek O, Tajsic T, Harcourt K, Scott K, Bashford-Rogers R, Helmy A, Reich DS, Belkaid Y, Lawley TD, McGavern DB, Clatworthy MR. Fitzpatrick Z, et al. Among authors: lawley td. Nature. 2020 Nov;587(7834):472-476. doi: 10.1038/s41586-020-2886-4. Epub 2020 Nov 4. Nature. 2020. PMID: 33149302 Free PMC article.
The Clostridium difficile spo0A gene is a persistence and transmission factor.
Deakin LJ, Clare S, Fagan RP, Dawson LF, Pickard DJ, West MR, Wren BW, Fairweather NF, Dougan G, Lawley TD. Deakin LJ, et al. Among authors: lawley td. Infect Immun. 2012 Aug;80(8):2704-11. doi: 10.1128/IAI.00147-12. Epub 2012 May 21. Infect Immun. 2012. PMID: 22615253 Free PMC article.
Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice.
Lawley TD, Clare S, Walker AW, Stares MD, Connor TR, Raisen C, Goulding D, Rad R, Schreiber F, Brandt C, Deakin LJ, Pickard DJ, Duncan SH, Flint HJ, Clark TG, Parkhill J, Dougan G. Lawley TD, et al. PLoS Pathog. 2012;8(10):e1002995. doi: 10.1371/journal.ppat.1002995. Epub 2012 Oct 25. PLoS Pathog. 2012. PMID: 23133377 Free PMC article.
Epithelial IL-22RA1-mediated fucosylation promotes intestinal colonization resistance to an opportunistic pathogen.
Pham TA, Clare S, Goulding D, Arasteh JM, Stares MD, Browne HP, Keane JA, Page AJ, Kumasaka N, Kane L, Mottram L, Harcourt K, Hale C, Arends MJ, Gaffney DJ; Sanger Mouse Genetics Project; Dougan G, Lawley TD. Pham TA, et al. Among authors: lawley td. Cell Host Microbe. 2014 Oct 8;16(4):504-16. doi: 10.1016/j.chom.2014.08.017. Epub 2014 Sep 25. Cell Host Microbe. 2014. PMID: 25263220 Free PMC article.
Systematic discovery of probiotics.
Forster SC, Lawley TD. Forster SC, et al. Among authors: lawley td. Nat Biotechnol. 2015 Jan;33(1):47-9. doi: 10.1038/nbt.3111. Nat Biotechnol. 2015. PMID: 25574637 No abstract available.
Transmission of the gut microbiota: spreading of health.
Browne HP, Neville BA, Forster SC, Lawley TD. Browne HP, et al. Among authors: lawley td. Nat Rev Microbiol. 2017 Sep;15(9):531-543. doi: 10.1038/nrmicro.2017.50. Epub 2017 Jun 12. Nat Rev Microbiol. 2017. PMID: 28603278 Free PMC article. Review.
132 results