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CSF1R inhibition depletes tumor-associated macrophages and attenuates tumor progression in a mouse sonic Hedgehog-Medulloblastoma model.
Tan IL, Arifa RDN, Rallapalli H, Kana V, Lao Z, Sanghrajka RM, Sumru Bayin N, Tanne A, Wojcinski A, Korshunov A, Bhardwaj N, Merad M, Turnbull DH, Lafaille JJ, Joyner AL. Tan IL, et al. Among authors: lafaille jj. Oncogene. 2021 Jan;40(2):396-407. doi: 10.1038/s41388-020-01536-0. Epub 2020 Nov 6. Oncogene. 2021. PMID: 33159168 Free PMC article.
Vasculature-associated fat macrophages readily adapt to inflammatory and metabolic challenges.
Silva HM, Báfica A, Rodrigues-Luiz GF, Chi J, Santos PDA, Reis BS, Hoytema van Konijnenburg DP, Crane A, Arifa RDN, Martin P, Mendes DAGB, Mansur DS, Torres VJ, Cadwell K, Cohen P, Mucida D, Lafaille JJ. Silva HM, et al. Among authors: lafaille jj. J Exp Med. 2019 Apr 1;216(4):786-806. doi: 10.1084/jem.20181049. Epub 2019 Mar 12. J Exp Med. 2019. PMID: 30862706 Free PMC article.
Protein kinase C-theta mediates negative feedback on regulatory T cell function.
Zanin-Zhorov A, Ding Y, Kumari S, Attur M, Hippen KL, Brown M, Blazar BR, Abramson SB, Lafaille JJ, Dustin ML. Zanin-Zhorov A, et al. Among authors: lafaille jj. Science. 2010 Apr 16;328(5976):372-6. doi: 10.1126/science.1186068. Epub 2010 Mar 25. Science. 2010. PMID: 20339032 Free PMC article.
Spleen plays a major role in DLL4-driven acute T-cell lymphoblastic leukemia.
Xiong H, Mancini M, Gobert M, Shen S, Furtado GC, Lira SA, Parkhurst CN, Garambois V, Brengues M, Tadokoro CE, Trimarchi T, Gómez-López G, Singh A, Khiabanian H, Minuzzo S, Indraccolo S, Lobry C, Aifantis I, Herranz D, Lafaille JJ, Maraver A. Xiong H, et al. Among authors: lafaille jj. Theranostics. 2021 Jan 1;11(4):1594-1608. doi: 10.7150/thno.48067. eCollection 2021. Theranostics. 2021. PMID: 33408769 Free PMC article.
91 results