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Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Barone M, Müller M, Chiha S, Ren J, Albat D, Soicke A, Dohmen S, Klein M, Bruns J, van Dinther M, Opitz R, Lindemann P, Beerbaum M, Motzny K, Roske Y, Schmieder P, Volkmer R, Nazaré M, Heinemann U, Oschkinat H, Ten Dijke P, Schmalz HG, Kühne R. Barone M, et al. Among authors: ren j. Proc Natl Acad Sci U S A. 2020 Nov 24;117(47):29684-29690. doi: 10.1073/pnas.2007213117. Epub 2020 Nov 12. Proc Natl Acad Sci U S A. 2020. PMID: 33184177 Free PMC article.
Targeting TGFβ signal transduction for cancer therapy.
Liu S, Ren J, Ten Dijke P. Liu S, et al. Among authors: ren j. Signal Transduct Target Ther. 2021 Jan 8;6(1):8. doi: 10.1038/s41392-020-00436-9. Signal Transduct Target Ther. 2021. PMID: 33414388 Free PMC article. Review.
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