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CCR5 inhibition in critical COVID-19 patients decreases inflammatory cytokines, increases CD8 T-cells, and decreases SARS-CoV2 RNA in plasma by day 14.
Patterson BK, Seethamraju H, Dhody K, Corley MJ, Kazempour K, Lalezari J, Pang APS, Sugai C, Mahyari E, Francisco EB, Pise A, Rodrigues H, Wu HL, Webb GM, Park BS, Kelly S, Pourhassan N, Lelic A, Kdouh L, Herrera M, Hall E, Bimber BN, Plassmeyer M, Gupta R, Alpan O, O'Halloran JA, Mudd PA, Akalin E, Ndhlovu LC, Sacha JB. Patterson BK, et al. Among authors: corley mj. Int J Infect Dis. 2021 Feb;103:25-32. doi: 10.1016/j.ijid.2020.10.101. Epub 2020 Nov 10. Int J Infect Dis. 2021. PMID: 33186704 Free PMC article.
Anti-α4β7 therapy targets lymphoid aggregates in the gastrointestinal tract of HIV-1-infected individuals.
Uzzan M, Tokuyama M, Rosenstein AK, Tomescu C, SahBandar IN, Ko HM, Leyre L, Chokola A, Kaplan-Lewis E, Rodriguez G, Seki A, Corley MJ, Aberg J, La Porte A, Park EY, Ueno H, Oikonomou I, Doron I, Iliev ID, Chen BK, Lui J, Schacker TW, Furtado GC, Lira SA, Colombel JF, Horowitz A, Lim JK, Chomont N, Rahman AH, Montaner LJ, Ndhlovu LC, Mehandru S. Uzzan M, et al. Among authors: corley mj. Sci Transl Med. 2018 Oct 3;10(461):eaau4711. doi: 10.1126/scitranslmed.aau4711. Sci Transl Med. 2018. PMID: 30282696 Free PMC article. Clinical Trial.
Lower Interferon Regulatory Factor-8 Expression in Peripheral Myeloid Cells Tracks With Adverse Central Nervous System Outcomes in Treated HIV Infection.
D'Antoni ML, Kallianpur KJ, Premeaux TA, Corley MJ, Fujita T, Laws EI, Ogata-Arakaki D, Chow DC, Khadka VS, Shikuma CM, Ndhlovu LC. D'Antoni ML, et al. Among authors: corley mj. Front Immunol. 2019 Nov 29;10:2789. doi: 10.3389/fimmu.2019.02789. eCollection 2019. Front Immunol. 2019. PMID: 31849969 Free PMC article.
Disruption of the CCL5/RANTES-CCR5 Pathway Restores Immune Homeostasis and Reduces Plasma Viral Load in Critical COVID-19.
Patterson BK, Seethamraju H, Dhody K, Corley MJ, Kazempour K, Lalezari JP, Pang AP, Sugai C, Francisco EB, Pise A, Rodrigues H, Ryou M, Wu HL, Webb GM, Park BS, Kelly S, Pourhassan N, Lelic A, Kdouh L, Herrera M, Hall E, Aklin E, Ndhlovu L, Sacha JB. Patterson BK, et al. Among authors: corley mj. medRxiv [Preprint]. 2020 May 5:2020.05.02.20084673. doi: 10.1101/2020.05.02.20084673. medRxiv. 2020. PMID: 32511656 Free PMC article. Preprint.
Effects of Brief Adjunctive Metformin Therapy in Virologically Suppressed HIV-Infected Adults on Polyfunctional HIV-Specific CD8 T Cell Responses to PD-L1 Blockade.
Chew GM, Padua AJP, Chow DC, Souza SA, Clements DM, Corley MJ, Pang APS, Alejandria MM, Gerschenson M, Shikuma CM, Ndhlovu LC. Chew GM, et al. Among authors: corley mj. AIDS Res Hum Retroviruses. 2021 Jan;37(1):24-33. doi: 10.1089/AID.2020.0172. Epub 2020 Nov 5. AIDS Res Hum Retroviruses. 2021. PMID: 33019813 Free PMC article. Clinical Trial.
Genome-wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID-19.
Corley MJ, Pang APS, Dody K, Mudd PA, Patterson BK, Seethamraju H, Bram Y, Peluso MJ, Torres L, Iyer NS, Premeaux TA, Yeung ST, Chandar V, Borczuk A, Schwartz RE, Henrich TJ, Deeks SG, Sacha JB, Ndhlovu LC. Corley MJ, et al. J Leukoc Biol. 2021 Jul;110(1):21-26. doi: 10.1002/JLB.5HI0720-466R. Epub 2021 Jan 19. J Leukoc Biol. 2021. PMID: 33464637 Free PMC article.
69 results