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Page 1
Digitoxigenin presents an effective and selective antileishmanial action against Leishmania infantum and is a potential therapeutic agent for visceral leishmaniasis.
Freitas CS, Oliveira-da-Silva JA, Lage DP, Costa RR, Mendonça DVC, Martins VT, Reis TAR, Antinarelli LMR, Machado AS, Tavares GSV, Ramos FF, Coelho VTS, Brito RCF, Ludolf F, Chávez-Fumagalli MA, Roatt BM, Ramos GS, Munkert J, Ottoni FM, Campana PRV, Humbert MV, Coimbra ES, Braga FC, Pádua RM, Coelho EAF. Freitas CS, et al. Among authors: munkert j. Parasitol Res. 2021 Jan;120(1):321-335. doi: 10.1007/s00436-020-06971-2. Epub 2020 Nov 16. Parasitol Res. 2021. PMID: 33191446 Free PMC article.
Production of the Cytotoxic Cardenolide Glucoevatromonoside by Semisynthesis and Biotransformation of Evatromonoside by a Digitalis lanata Cell Culture.
Munkert J, Santiago Franco M, Nolte E, Thaís Silva I, Oliveira Castilho R, Melo Ottoni F, Schneider NFZ, Oliveira MC, Taubert H, Bauer W, Andrade SF, Alves RJ, Simões CMO, Braga FC, Kreis W, de Pádua RM. Munkert J, et al. Planta Med. 2017 Aug;83(12-13):1035-1043. doi: 10.1055/s-0043-109557. Epub 2017 May 9. Planta Med. 2017. PMID: 28486743
Cytotoxic and cytostatic effects of digitoxigenin monodigitoxoside (DGX) in human lung cancer cells and its link to Na,K-ATPase.
Schneider NFZ, Persich L, Rocha SC, Ramos ACP, Cortes VF, Silva IT, Munkert J, Pádua RM, Kreis W, Taranto AG, Barbosa LA, Braga FC, Simões CMO. Schneider NFZ, et al. Among authors: munkert j. Biomed Pharmacother. 2018 Jan;97:684-696. doi: 10.1016/j.biopha.2017.10.128. Epub 2017 Nov 6. Biomed Pharmacother. 2018. PMID: 29101813
Cardiac Glycoside Glucoevatromonoside Induces Cancer Type-Specific Cell Death.
Schneider NFZ, Cerella C, Lee JY, Mazumder A, Kim KR, de Carvalho A, Munkert J, Pádua RM, Kreis W, Kim KW, Christov C, Dicato M, Kim HJ, Han BW, Braga FC, Simões CMO, Diederich M. Schneider NFZ, et al. Among authors: munkert j. Front Pharmacol. 2018 Mar 1;9:70. doi: 10.3389/fphar.2018.00070. eCollection 2018. Front Pharmacol. 2018. PMID: 29545747 Free PMC article.
Cytotoxicity of AMANTADIG - a semisynthetic digitoxigenin derivative - alone and in combination with docetaxel in human hormone-refractory prostate cancer cells and its effect on Na+/K+-ATPase inhibition.
Silva IT, Munkert J, Nolte E, Schneider NFZ, Rocha SC, Ramos ACP, Kreis W, Braga FC, de Pádua RM, Taranto AG, Cortes V, Barbosa LA, Wach S, Taubert H, Simões CMO. Silva IT, et al. Among authors: munkert j. Biomed Pharmacother. 2018 Nov;107:464-474. doi: 10.1016/j.biopha.2018.08.028. Epub 2018 Aug 11. Biomed Pharmacother. 2018. PMID: 30107342
Potential anti-herpes and cytotoxic action of novel semisynthetic digitoxigenin-derivatives.
Boff L, Munkert J, Ottoni FM, Zanchett Schneider NF, Ramos GS, Kreis W, Fernandes de Andrade S, Dias de Souza Filho J, Braga FC, Alves RJ, Maia de Pádua R, Oliveira Simões CM. Boff L, et al. Among authors: munkert j. Eur J Med Chem. 2019 Apr 1;167:546-561. doi: 10.1016/j.ejmech.2019.01.076. Epub 2019 Feb 2. Eur J Med Chem. 2019. PMID: 30798081
New 99mTc-Labeled Digitoxigenin Derivative for Cancer Cell Identification.
Munkert J, Gomes ER, Marostica LL, Cota BB, Lopes CLM, Andrade SF, Filho JDS, Alves RJ, Oliveira MC, Braga FC, Simões CMO, Pádua RM, de Barros ALB. Munkert J, et al. ACS Omega. 2019 Dec 11;4(26):22048-22056. doi: 10.1021/acsomega.9b03167. eCollection 2019 Dec 24. ACS Omega. 2019. PMID: 31891085 Free PMC article.
30 results