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Page 1
Gs/Gq signaling switch in β cells defines incretin effectiveness in diabetes.
Oduori OS, Murao N, Shimomura K, Takahashi H, Zhang Q, Dou H, Sakai S, Minami K, Chanclon B, Guida C, Kothegala L, Tolö J, Maejima Y, Yokoi N, Minami Y, Miki T, Rorsman P, Seino S. Oduori OS, et al. Among authors: tolo j. J Clin Invest. 2020 Dec 1;130(12):6639-6655. doi: 10.1172/JCI140046. J Clin Invest. 2020. PMID: 33196462 Free PMC article.
Hindbrain insulin controls feeding behavior.
Eerola K, Longo F, Reinbothe TM, Richard JE, Shevchouk OT, López-Ferreras L, Mishra D, Asker M, Tolö J, Miranda C, Musovic S, Olofsson CS, Rorsman P, Skibicka KP. Eerola K, et al. Among authors: tolo j. Mol Metab. 2022 Dec;66:101614. doi: 10.1016/j.molmet.2022.101614. Epub 2022 Oct 13. Mol Metab. 2022. PMID: 36244663 Free PMC article.
Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics.
Akerboom J, Carreras Calderón N, Tian L, Wabnig S, Prigge M, Tolö J, Gordus A, Orger MB, Severi KE, Macklin JJ, Patel R, Pulver SR, Wardill TJ, Fischer E, Schüler C, Chen TW, Sarkisyan KS, Marvin JS, Bargmann CI, Kim DS, Kügler S, Lagnado L, Hegemann P, Gottschalk A, Schreiter ER, Looger LL. Akerboom J, et al. Among authors: tolo j. Front Mol Neurosci. 2013 Mar 4;6:2. doi: 10.3389/fnmol.2013.00002. eCollection 2013. Front Mol Neurosci. 2013. PMID: 23459413 Free PMC article.
Pathophysiological Consequences of Neuronal α-Synuclein Overexpression: Impacts on Ion Homeostasis, Stress Signaling, Mitochondrial Integrity, and Electrical Activity.
Tolö J, Taschenberger G, Leite K, Stahlberg MA, Spehlbrink G, Kues J, Munari F, Capaldi S, Becker S, Zweckstetter M, Dean C, Bähr M, Kügler S. Tolö J, et al. Front Mol Neurosci. 2018 Mar 7;11:49. doi: 10.3389/fnmol.2018.00049. eCollection 2018. Front Mol Neurosci. 2018. PMID: 29563864 Free PMC article.
Loss of electrical β-cell to δ-cell coupling underlies impaired hypoglycaemia-induced glucagon secretion in type-1 diabetes.
Hill TG, Gao R, Benrick A, Kothegala L, Rorsman N, Santos C, Acreman S, Briant LJ, Dou H, Gandasi NR, Guida C, Haythorne E, Wallace M, Knudsen JG, Miranda C, Tolö J, Clark A, Davison L, Størling J, Tarasov A, Ashcroft FM, Rorsman P, Zhang Q. Hill TG, et al. Among authors: tolo j. Nat Metab. 2024 Nov;6(11):2070-2081. doi: 10.1038/s42255-024-01139-z. Epub 2024 Sep 23. Nat Metab. 2024. PMID: 39313541 Free PMC article.
Cardiac Plin5 interacts with SERCA2 and promotes calcium handling and cardiomyocyte contractility.
Cinato M, Mardani I, Miljanovic A, Drevinge C, Laudette M, Bollano E, Henricsson M, Tolö J, Bauza Thorbrügge M, Levin M, Lindbom M, Arif M, Pacher P, Andersson L, Olofsson CS, Borén J, Levin MC. Cinato M, et al. Among authors: tolo j. Life Sci Alliance. 2023 Jan 30;6(4):e202201690. doi: 10.26508/lsa.202201690. Print 2023 Apr. Life Sci Alliance. 2023. PMID: 36717246 Free PMC article.