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C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38α activation, while it impairs tumor growth through p38α-independent mechanisms.
Priego N, Arechederra M, Sequera C, Bragado P, Vázquez-Carballo A, Gutiérrez-Uzquiza Á, Martín-Granado V, Ventura JJ, Kazanietz MG, Guerrero C, Porras A. Priego N, et al. Among authors: sequera c. Oncotarget. 2016 Jul 19;7(29):45060-45078. doi: 10.18632/oncotarget.9911. Oncotarget. 2016. PMID: 27286263 Free PMC article.
p38 MAPK down-regulates fibulin 3 expression through methylation of gene regulatory sequences: role in migration and invasion.
Arechederra M, Priego N, Vázquez-Carballo A, Sequera C, Gutiérrez-Uzquiza Á, Cerezo-Guisado MI, Ortiz-Rivero S, Roncero C, Cuenda A, Guerrero C, Porras A. Arechederra M, et al. Among authors: sequera c. J Biol Chem. 2015 Feb 13;290(7):4383-97. doi: 10.1074/jbc.M114.582239. Epub 2014 Dec 29. J Biol Chem. 2015. PMID: 25548290 Free PMC article.
C3G promotes a selective release of angiogenic factors from activated mouse platelets to regulate angiogenesis and tumor metastasis.
Martín-Granado V, Ortiz-Rivero S, Carmona R, Gutiérrez-Herrero S, Barrera M, San-Segundo L, Sequera C, Perdiguero P, Lozano F, Martín-Herrero F, González-Porras JR, Muñoz-Chápuli R, Porras A, Guerrero C. Martín-Granado V, et al. Among authors: sequera c. Oncotarget. 2017 Nov 6;8(67):110994-111011. doi: 10.18632/oncotarget.22339. eCollection 2017 Dec 19. Oncotarget. 2017. PMID: 29340032 Free PMC article.
18 results