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Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer's disease via H2O2- production.
Chun H, Im H, Kang YJ, Kim Y, Shin JH, Won W, Lim J, Ju Y, Park YM, Kim S, Lee SE, Lee J, Woo J, Hwang Y, Cho H, Jo S, Park JH, Kim D, Kim DY, Seo JS, Gwag BJ, Kim YS, Park KD, Kaang BK, Cho H, Ryu H, Lee CJ. Chun H, et al. Among authors: hwang y. Nat Neurosci. 2020 Dec;23(12):1555-1566. doi: 10.1038/s41593-020-00735-y. Epub 2020 Nov 16. Nat Neurosci. 2020. PMID: 33199896
GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease.
Jo S, Yarishkin O, Hwang YJ, Chun YE, Park M, Woo DH, Bae JY, Kim T, Lee J, Chun H, Park HJ, Lee DY, Hong J, Kim HY, Oh SJ, Park SJ, Lee H, Yoon BE, Kim Y, Jeong Y, Shim I, Bae YC, Cho J, Kowall NW, Ryu H, Hwang E, Kim D, Lee CJ. Jo S, et al. Among authors: hwang e, hwang yj. Nat Med. 2014 Aug;20(8):886-96. doi: 10.1038/nm.3639. Epub 2014 Jun 29. Nat Med. 2014. PMID: 24973918 Free PMC article.
Aberrant Tonic Inhibition of Dopaminergic Neuronal Activity Causes Motor Symptoms in Animal Models of Parkinson's Disease.
Heo JY, Nam MH, Yoon HH, Kim J, Hwang YJ, Won W, Woo DH, Lee JA, Park HJ, Jo S, Lee MJ, Kim S, Shim JE, Jang DP, Kim KI, Huh SH, Jeong JY, Kowall NW, Lee J, Im H, Park JH, Jang BK, Park KD, Lee HJ, Shin H, Cho IJ, Hwang EM, Kim Y, Kim HY, Oh SJ, Lee SE, Paek SH, Yoon JH, Jin BK, Kweon GR, Shim I, Hwang O, Ryu H, Jeon SR, Lee CJ. Heo JY, et al. Among authors: hwang yj, hwang o, hwang em. Curr Biol. 2020 Jan 20;30(2):276-291.e9. doi: 10.1016/j.cub.2019.11.079. Epub 2020 Jan 9. Curr Biol. 2020. PMID: 31928877 Free article.
Transcriptome analyses of chronic traumatic encephalopathy show alterations in protein phosphatase expression associated with tauopathy.
Seo JS, Lee S, Shin JY, Hwang YJ, Cho H, Yoo SK, Kim Y, Lim S, Kim YK, Hwang EM, Kim SH, Kim CH, Hyeon SJ, Yun JY, Kim J, Kim Y, Alvarez VE, Stein TD, Lee J, Kim DJ, Kim JI, Kowall NW, Ryu H, McKee AC. Seo JS, et al. Among authors: hwang yj, hwang em. Exp Mol Med. 2017 May 19;49(5):e333. doi: 10.1038/emm.2017.56. Exp Mol Med. 2017. PMID: 28524178 Free PMC article.
4,781 results