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S327 phosphorylation of the presynaptic protein SEPTIN5 increases in the early stages of neurofibrillary pathology and alters the functionality of SEPTIN5.
Ferreira CB, Marttinen M, Coelho JE, Paldanius KMA, Takalo M, Mäkinen P, Leppänen L, Miranda-Lourenço C, Fonseca-Gomes J, Tanqueiro SR, Vaz SH, Belo RF, Sebastião AM, Leinonen V, Soininen H, Pike I, Haapasalo A, Lopes LV, de Mendonça A, Diógenes MJ, Hiltunen M. Ferreira CB, et al. Among authors: leppanen l. Neurobiol Dis. 2022 Feb;163:105603. doi: 10.1016/j.nbd.2021.105603. Epub 2021 Dec 24. Neurobiol Dis. 2022. PMID: 34954322 Free article.
Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques.
Natunen T, Martiskainen H, Marttinen M, Gabbouj S, Koivisto H, Kemppainen S, Kaipainen S, Takalo M, Svobodová H, Leppänen L, Kemiläinen B, Ryhänen S, Kuulasmaa T, Rahunen E, Juutinen S, Mäkinen P, Miettinen P, Rauramaa T, Pihlajamäki J, Haapasalo A, Leinonen V, Tanila H, Hiltunen M. Natunen T, et al. Among authors: leppanen l. Mol Neurodegener. 2020 Nov 10;15(1):66. doi: 10.1186/s13024-020-00415-2. Mol Neurodegener. 2020. PMID: 33168021 Free PMC article.
Incidence and Prevalence of Early-Onset Dementia in Finland.
Krüger J, Aaltonen M, Aho K, Heikkinen S, Kivisild A, Lehtonen A, Leppänen L, Rinnankoski I, Soppela H, Tervonen L, Suhonen NM, Haapasalo A, Portaankorva AM, Mäki-Petäjä-Leinonen A, Hartikainen P, Katisko K, Solje E. Krüger J, et al. Among authors: leppanen l. Neurology. 2024 Aug 27;103(4):e209654. doi: 10.1212/WNL.0000000000209654. Epub 2024 Jul 24. Neurology. 2024. PMID: 39047214 Free PMC article.
Early appearance of thyroid autoimmunity in children followed from birth for type 1 diabetes risk.
Jonsdottir B, Clasen JL, Vehik K, Lernmark Å, Lundgren M, Bonifacio E, Schatz D, Ziegler AG, Hagopian W, Rewers M, McIndoe R, Toppari J, Krischer J, Akolkar B, Steck A, Veijola R, Haller MJ, Elding Larsson H; TEDDY Study Group. Jonsdottir B, et al. J Clin Endocrinol Metab. 2024 Jul 12:dgae478. doi: 10.1210/clinem/dgae478. Online ahead of print. J Clin Endocrinol Metab. 2024. PMID: 38996042
Intake of B vitamins and the risk of developing islet autoimmunity and type 1 diabetes in the TEDDY study.
Hakola L, Mramba LK, Uusitalo U, Andrén Aronsson C, Hummel S, Niinistö S, Erlund I, Yang J, Rewers MJ, Akolkar B, McIndoe RA, Rich SS, Hagopian WA, Ziegler A, Lernmark Å, Toppari J, Krischer JP, Norris JM, Virtanen SM; TEDDY Study Group. Hakola L, et al. Eur J Nutr. 2024 Jun;63(4):1329-1338. doi: 10.1007/s00394-024-03346-6. Epub 2024 Feb 27. Eur J Nutr. 2024. PMID: 38413484 Free PMC article.
HLA Genotype and Probiotics Modify the Association Between Timing of Solid Food Introduction and Islet Autoimmunity in the TEDDY Study.
Uusitalo U, Mramba LK, Aronsson CA, Vehik K, Yang J, Hummel S, Lernmark Å, Rewers M, Hagopian W, McIndoe R, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Virtanen SM, Norris JM; TEDDY Study Group; TEDDY Study Group. Uusitalo U, et al. Diabetes Care. 2023 Oct 1;46(10):1839-1847. doi: 10.2337/dc23-0417. Diabetes Care. 2023. PMID: 37579501 Free PMC article.
SARS-CoV-2 - No Increased Islet Autoimmunity or Type 1 Diabetes in Teens.
Krischer JP, Lernmark Å, Hagopian WA, Rewers MJ, McIndoe R, Toppari J, Ziegler AG, Akolkar B; TEDDY Study Group. Krischer JP, et al. N Engl J Med. 2023 Aug 3;389(5):474-475. doi: 10.1056/NEJMc2216477. N Engl J Med. 2023. PMID: 37530831 Free PMC article. No abstract available.
33 results