He Y - Search Results

1

RACK1 Mediates NLRP3 Inflammasome Activation by Promoting NLRP3 Active Conformation and Inflammasome Assembly.

Duan Y, Zhang L, Angosto-Bazarra D, Pelegrín P, Núñez G, He Y. Duan Y, et al. Among authors: he y. Cell Rep. 2020 Nov 17;33(7):108405. doi: 10.1016/j.celrep.2020.108405. Cell Rep. 2020. PMID: 33207200 Free PMC article.

2

TLR agonists stimulate Nlrp3-dependent IL-1β production independently of the purinergic P2X7 receptor in dendritic cells and in vivo.

He Y, Franchi L, Núñez G. He Y, et al. J Immunol. 2013 Jan 1;190(1):334-9. doi: 10.4049/jimmunol.1202737. Epub 2012 Dec 7. J Immunol. 2013. PMID: 23225887 Free PMC article.

3

The protein kinase PKR is critical for LPS-induced iNOS production but dispensable for inflammasome activation in macrophages.

He Y, Franchi L, Núñez G. He Y, et al. Eur J Immunol. 2013 May;43(5):1147-52. doi: 10.1002/eji.201243187. Epub 2013 Mar 15. Eur J Immunol. 2013. PMID: 23401008 Free PMC article.

4

3,4-methylenedioxy-β-nitrostyrene inhibits NLRP3 inflammasome activation by blocking assembly of the inflammasome.

He Y, Varadarajan S, Muñoz-Planillo R, Burberry A, Nakamura Y, Núñez G. He Y, et al. J Biol Chem. 2014 Jan 10;289(2):1142-50. doi: 10.1074/jbc.M113.515080. Epub 2013 Nov 21. J Biol Chem. 2014. PMID: 24265316 Free PMC article.

5

Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkcδ.

Suzuki S, Franchi L, He Y, Muñoz-Planillo R, Mimuro H, Suzuki T, Sasakawa C, Núñez G. Suzuki S, et al. Among authors: he y. PLoS Pathog. 2014 Feb 6;10(2):e1003926. doi: 10.1371/journal.ppat.1003926. eCollection 2014 Feb. PLoS Pathog. 2014. PMID: 24516390 Free PMC article.

6

Caspase-11 Requires the Pannexin-1 Channel and the Purinergic P2X7 Pore to Mediate Pyroptosis and Endotoxic Shock.

Yang D, He Y, Muñoz-Planillo R, Liu Q, Núñez G. Yang D, et al. Among authors: he y. Immunity. 2015 Nov 17;43(5):923-32. doi: 10.1016/j.immuni.2015.10.009. Epub 2015 Nov 10. Immunity. 2015. PMID: 26572062 Free PMC article.

7

NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux.

He Y, Zeng MY, Yang D, Motro B, Núñez G. He Y, et al. Nature. 2016 Feb 18;530(7590):354-7. doi: 10.1038/nature16959. Epub 2016 Jan 27. Nature. 2016. PMID: 26814970 Free PMC article.

8

Mechanism and Regulation of NLRP3 Inflammasome Activation.

He Y, Hara H, Núñez G. He Y, et al. Trends Biochem Sci. 2016 Dec;41(12):1012-1021. doi: 10.1016/j.tibs.2016.09.002. Epub 2016 Sep 23. Trends Biochem Sci. 2016. PMID: 27669650 Free PMC article. Review.

9

The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation.

Kelley N, Jeltema D, Duan Y, He Y. Kelley N, et al. Among authors: he y. Int J Mol Sci. 2019 Jul 6;20(13):3328. doi: 10.3390/ijms20133328. Int J Mol Sci. 2019. PMID: 31284572 Free PMC article. Review.

10

Role of the NLRP3 inflammasome in neurodegenerative diseases and therapeutic implications.

Duan Y, Kelley N, He Y. Duan Y, et al. Among authors: he y. Neural Regen Res. 2020 Jul;15(7):1249-1250. doi: 10.4103/1673-5374.272576. Neural Regen Res. 2020. PMID: 31960806 Free PMC article. No abstract available.

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