Ye L - Search Results

1

Induction of therapeutic levels of HbF in genome-edited primary β⁰ 39-thalassaemia haematopoietic stem and progenitor cells.

Mingoia M, Caria CA, Ye L, Asunis I, Marongiu MF, Manunza L, Sollaino MC, Wang J, Cabriolu A, Kurita R, Nakamura Y, Cucca F, Kan YW, Marini MG, Moi P. Mingoia M, et al. Among authors: ye l. Br J Haematol. 2021 Jan;192(2):395-404. doi: 10.1111/bjh.17167. Epub 2020 Nov 20. Br J Haematol. 2021. PMID: 33216968 Free article.

2

Correction of the sickle cell mutation in embryonic stem cells.

Chang JC, Ye L, Kan YW. Chang JC, et al. Among authors: ye l. Proc Natl Acad Sci U S A. 2006 Jan 24;103(4):1036-40. doi: 10.1073/pnas.0510177103. Epub 2006 Jan 11. Proc Natl Acad Sci U S A. 2006. PMID: 16407095 Free PMC article.

3

High oxygen environment during pregnancy rescues sickle cell anemia mice from prenatal death.

Ye L, Chang JC, Lu R, Kan YW. Ye L, et al. Blood Cells Mol Dis. 2008 Jul-Aug;41(1):67-72. doi: 10.1016/j.bcmd.2007.12.002. Epub 2008 Jan 22. Blood Cells Mol Dis. 2008. PMID: 18207438

4

Induced pluripotent stem cells offer new approach to therapy in thalassemia and sickle cell anemia and option in prenatal diagnosis in genetic diseases.

Ye L, Chang JC, Lin C, Sun X, Yu J, Kan YW. Ye L, et al. Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9826-30. doi: 10.1073/pnas.0904689106. Epub 2009 May 29. Proc Natl Acad Sci U S A. 2009. PMID: 19482945 Free PMC article.

5

Generation of induced pluripotent stem cells using site-specific integration with phage integrase.

Ye L, Chang JC, Lin C, Qi Z, Yu J, Kan YW. Ye L, et al. Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19467-72. doi: 10.1073/pnas.1012677107. Epub 2010 Oct 25. Proc Natl Acad Sci U S A. 2010. PMID: 20974949 Free PMC article.

6

Blood cell-derived induced pluripotent stem cells free of reprogramming factors generated by Sendai viral vectors.

Ye L, Muench MO, Fusaki N, Beyer AI, Wang J, Qi Z, Yu J, Kan YW. Ye L, et al. Stem Cells Transl Med. 2013 Aug;2(8):558-66. doi: 10.5966/sctm.2013-0006. Epub 2013 Jul 11. Stem Cells Transl Med. 2013. PMID: 23847002 Free PMC article.

7

Seamless modification of wild-type induced pluripotent stem cells to the natural CCR5Δ32 mutation confers resistance to HIV infection.

Ye L, Wang J, Beyer AI, Teque F, Cradick TJ, Qi Z, Chang JC, Bao G, Muench MO, Yu J, Levy JA, Kan YW. Ye L, et al. Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):9591-6. doi: 10.1073/pnas.1407473111. Epub 2014 Jun 9. Proc Natl Acad Sci U S A. 2014. PMID: 24927590 Free PMC article.

8

Seamless gene correction of β-thalassemia mutations in patient-specific iPSCs using CRISPR/Cas9 and piggyBac.

Xie F, Ye L, Chang JC, Beyer AI, Wang J, Muench MO, Kan YW. Xie F, et al. Among authors: ye l. Genome Res. 2014 Sep;24(9):1526-33. doi: 10.1101/gr.173427.114. Epub 2014 Aug 5. Genome Res. 2014. PMID: 25096406 Free PMC article.

9

Reversible Immortalization Enables Seamless Transdifferentiation of Primary Fibroblasts into Other Lineage Cells.

Xie F, Gong K, Li K, Zhang M, Chang JC, Jiang S, Ye L, Wang J, Tan Y, Kan YW. Xie F, et al. Among authors: ye l. Stem Cells Dev. 2016 Aug 15;25(16):1243-8. doi: 10.1089/scd.2016.0035. Epub 2016 Jul 28. Stem Cells Dev. 2016. PMID: 27328768 Free PMC article.

10

Genome editing using CRISPR-Cas9 to create the HPFH genotype in HSPCs: An approach for treating sickle cell disease and β-thalassemia.

Ye L, Wang J, Tan Y, Beyer AI, Xie F, Muench MO, Kan YW. Ye L, et al. Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):10661-5. doi: 10.1073/pnas.1612075113. Epub 2016 Sep 6. Proc Natl Acad Sci U S A. 2016. PMID: 27601644 Free PMC article.

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