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Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease.
Wang M, Li A, Sekiya M, Beckmann ND, Quan X, Schrode N, Fernando MB, Yu A, Zhu L, Cao J, Lyu L, Horgusluoglu E, Wang Q, Guo L, Wang YS, Neff R, Song WM, Wang E, Shen Q, Zhou X, Ming C, Ho SM, Vatansever S, Kaniskan HÜ, Jin J, Zhou MM, Ando K, Ho L, Slesinger PA, Yue Z, Zhu J, Katsel P, Gandy S, Ehrlich ME, Fossati V, Noggle S, Cai D, Haroutunian V, Iijima KM, Schadt E, Brennand KJ, Zhang B. Wang M, et al. Among authors: zhou x, zhou mm. Neuron. 2021 Jan 20;109(2):257-272.e14. doi: 10.1016/j.neuron.2020.11.002. Epub 2020 Nov 24. Neuron. 2021. PMID: 33238137 Free PMC article.
Targeting the SIN3A-PF1 interaction inhibits epithelial to mesenchymal transition and maintenance of a stem cell phenotype in triple negative breast cancer.
Bansal N, Petrie K, Christova R, Chung CY, Leibovitch BA, Howell L, Gil V, Sbirkov Y, Lee E, Wexler J, Ariztia EV, Sharma R, Zhu J, Bernstein E, Zhou MM, Zelent A, Farias E, Waxman S. Bansal N, et al. Among authors: zhou mm. Oncotarget. 2015 Oct 27;6(33):34087-105. doi: 10.18632/oncotarget.6048. Oncotarget. 2015. PMID: 26460951 Free PMC article.
Vitamin B12 modulates Parkinson's disease LRRK2 kinase activity through allosteric regulation and confers neuroprotection.
Schaffner A, Li X, Gomez-Llorente Y, Leandrou E, Memou A, Clemente N, Yao C, Afsari F, Zhi L, Pan N, Morohashi K, Hua X, Zhou MM, Wang C, Zhang H, Chen SG, Elliott CJ, Rideout H, Ubarretxena-Belandia I, Yue Z. Schaffner A, et al. Among authors: zhou mm. Cell Res. 2019 Apr;29(4):313-329. doi: 10.1038/s41422-019-0153-8. Epub 2019 Mar 11. Cell Res. 2019. PMID: 30858560 Free PMC article.
The bromodomain: from epigenome reader to druggable target.
Sanchez R, Meslamani J, Zhou MM. Sanchez R, et al. Among authors: zhou mm. Biochim Biophys Acta. 2014 Aug;1839(8):676-85. doi: 10.1016/j.bbagrm.2014.03.011. Epub 2014 Mar 28. Biochim Biophys Acta. 2014. PMID: 24686119 Free PMC article. Review.
287 results