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EMT Transcription Factor ZEB1 Represses the Mutagenic POLθ-Mediated End-Joining Pathway in Breast Cancers.
Prodhomme MK, Pommier RM, Franchet C, Fauvet F, Bergoglio V, Brousset P, Morel AP, Brunac AC, Devouassoux-Shisheboran M, Petrilli V, Moyret-Lalle C, Hoffmann JS, Puisieux A, Tissier A. Prodhomme MK, et al. Among authors: tissier a. Cancer Res. 2021 Mar 15;81(6):1595-1606. doi: 10.1158/0008-5472.CAN-20-2626. Epub 2020 Nov 25. Cancer Res. 2021. PMID: 33239429
A stemness-related ZEB1-MSRB3 axis governs cellular pliancy and breast cancer genome stability.
Morel AP, Ginestier C, Pommier RM, Cabaud O, Ruiz E, Wicinski J, Devouassoux-Shisheboran M, Combaret V, Finetti P, Chassot C, Pinatel C, Fauvet F, Saintigny P, Thomas E, Moyret-Lalle C, Lachuer J, Despras E, Jauffret JL, Bertucci F, Guitton J, Wierinckx A, Wang Q, Radosevic-Robin N, Penault-Llorca F, Cox DG, Hollande F, Ansieau S, Caramel J, Birnbaum D, Vigneron AM, Tissier A, Charafe-Jauffret E, Puisieux A. Morel AP, et al. Among authors: tissier a. Nat Med. 2017 May;23(5):568-578. doi: 10.1038/nm.4323. Epub 2017 Apr 10. Nat Med. 2017. PMID: 28394329
Opposite Roles for ZEB1 and TMEJ in the Regulation of Breast Cancer Genome Stability.
Prodhomme MK, Péricart S, Pommier RM, Morel AP, Brunac AC, Franchet C, Moyret-Lalle C, Brousset P, Puisieux A, Hoffmann JS, Tissier A. Prodhomme MK, et al. Among authors: tissier a. Front Cell Dev Biol. 2021 Aug 12;9:727429. doi: 10.3389/fcell.2021.727429. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34458275 Free PMC article. Review.
The cell-of-origin dictates the genomic landscape of breast cancers.
Puisieux A, Pommier RM, Tissier A, Morel AP. Puisieux A, et al. Among authors: tissier a. Mol Cell Oncol. 2017 Jun 16;4(4):e1338931. doi: 10.1080/23723556.2017.1338931. eCollection 2017. Mol Cell Oncol. 2017. PMID: 28868351 Free PMC article.
EMT inducers catalyze malignant transformation of mammary epithelial cells and drive tumorigenesis towards claudin-low tumors in transgenic mice.
Morel AP, Hinkal GW, Thomas C, Fauvet F, Courtois-Cox S, Wierinckx A, Devouassoux-Shisheboran M, Treilleux I, Tissier A, Gras B, Pourchet J, Puisieux I, Browne GJ, Spicer DB, Lachuer J, Ansieau S, Puisieux A. Morel AP, et al. Among authors: tissier a. PLoS Genet. 2012;8(5):e1002723. doi: 10.1371/journal.pgen.1002723. Epub 2012 May 24. PLoS Genet. 2012. PMID: 22654675 Free PMC article.
126 results