Zwicker K - Search Results

1

Essential role of accessory subunit LYRM6 in the mechanism of mitochondrial complex I.

Galemou Yoga E, Parey K, Djurabekova A, Haapanen O, Siegmund K, Zwicker K, Sharma V, Zickermann V, Angerer H. Galemou Yoga E, et al. Among authors: zwicker k. Nat Commun. 2020 Nov 26;11(1):6008. doi: 10.1038/s41467-020-19778-7. Nat Commun. 2020. PMID: 33243981 Free PMC article.

2

A scaffold of accessory subunits links the peripheral arm and the distal proton-pumping module of mitochondrial complex I.

Angerer H, Zwicker K, Wumaier Z, Sokolova L, Heide H, Steger M, Kaiser S, Nübel E, Brutschy B, Radermacher M, Brandt U, Zickermann V. Angerer H, et al. Among authors: zwicker k. Biochem J. 2011 Jul 15;437(2):279-88. doi: 10.1042/BJ20110359. Biochem J. 2011. PMID: 21545356 Free PMC article.

3

The LYR protein subunit NB4M/NDUFA6 of mitochondrial complex I anchors an acyl carrier protein and is essential for catalytic activity.

Angerer H, Radermacher M, Mańkowska M, Steger M, Zwicker K, Heide H, Wittig I, Brandt U, Zickermann V. Angerer H, et al. Among authors: zwicker k. Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5207-12. doi: 10.1073/pnas.1322438111. Epub 2014 Mar 24. Proc Natl Acad Sci U S A. 2014. PMID: 24706851 Free PMC article.

4

Accessory subunit NUYM (NDUFS4) is required for stability of the electron input module and activity of mitochondrial complex I.

Kahlhöfer F, Kmita K, Wittig I, Zwicker K, Zickermann V. Kahlhöfer F, et al. Among authors: zwicker k. Biochim Biophys Acta Bioenerg. 2017 Feb;1858(2):175-181. doi: 10.1016/j.bbabio.2016.11.010. Epub 2016 Nov 19. Biochim Biophys Acta Bioenerg. 2017. PMID: 27871794 Free article.

5

Locking loop movement in the ubiquinone pocket of complex I disengages the proton pumps.

Cabrera-Orefice A, Yoga EG, Wirth C, Siegmund K, Zwicker K, Guerrero-Castillo S, Zickermann V, Hunte C, Brandt U. Cabrera-Orefice A, et al. Among authors: zwicker k. Nat Commun. 2018 Oct 29;9(1):4500. doi: 10.1038/s41467-018-06955-y. Nat Commun. 2018. PMID: 30374105 Free PMC article.

6

Yarrowia lipolytica, a yeast genetic system to study mitochondrial complex I.

Kerscher S, Dröse S, Zwicker K, Zickermann V, Brandt U. Kerscher S, et al. Among authors: zwicker k. Biochim Biophys Acta. 2002 Sep 10;1555(1-3):83-91. doi: 10.1016/s0005-2728(02)00259-1. Biochim Biophys Acta. 2002. PMID: 12206896 Free article. Review.

7

Proton pumping by NADH:ubiquinone oxidoreductase. A redox driven conformational change mechanism?

Brandt U, Kerscher S, Dröse S, Zwicker K, Zickermann V. Brandt U, et al. Among authors: zwicker k. FEBS Lett. 2003 Jun 12;545(1):9-17. doi: 10.1016/s0014-5793(03)00387-9. FEBS Lett. 2003. PMID: 12788486 Free article. Review.

8

Histidine 129 in the 75-kDa subunit of mitochondrial complex I from Yarrowia lipolytica is not a ligand for [Fe4S4] cluster N5 but is required for catalytic activity.

Waletko A, Zwicker K, Abdrakhmanova A, Zickermann V, Brandt U, Kerscher S. Waletko A, et al. Among authors: zwicker k. J Biol Chem. 2005 Feb 18;280(7):5622-5. doi: 10.1074/jbc.M411488200. Epub 2004 Nov 30. J Biol Chem. 2005. PMID: 15572358 Free article.

9

Tight binding of NADPH to the 39-kDa subunit of complex I is not required for catalytic activity but stabilizes the multiprotein complex.

Abdrakhmanova A, Zwicker K, Kerscher S, Zickermann V, Brandt U. Abdrakhmanova A, et al. Among authors: zwicker k. Biochim Biophys Acta. 2006 Dec;1757(12):1676-82. doi: 10.1016/j.bbabio.2006.09.003. Epub 2006 Sep 19. Biochim Biophys Acta. 2006. PMID: 17046710 Free article.

10

Characterization of a subcomplex of mitochondrial NADH:ubiquinone oxidoreductase (complex I) lacking the flavoprotein part of the N-module.

Zickermann V, Zwicker K, Tocilescu MA, Kerscher S, Brandt U. Zickermann V, et al. Among authors: zwicker k. Biochim Biophys Acta. 2007 May;1767(5):393-400. doi: 10.1016/j.bbabio.2007.03.005. Epub 2007 Mar 15. Biochim Biophys Acta. 2007. PMID: 17448440 Free article.

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