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HIV-1 evades a Gag mutation that abrogates killer cell immunoglobulin-like receptor binding and disinhibits natural killer cells in infected individuals with KIR2DL2+/HLA-C*03: 04+ genotype.
Ziegler MC, Naidoo K, Chapel A, Nkotwana S, Mann J, Mncube Z, Ismael N, Goulder P, Ndung'u T, Altfeld M, Thobakgale CF. Ziegler MC, et al. Among authors: chapel a. AIDS. 2021 Jan 1;35(1):151-154. doi: 10.1097/QAD.0000000000002721. AIDS. 2021. PMID: 33273184 Free PMC article.
Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16.
Gunn B, Schneider J, Shansab M, Bastian AR, Fahrbach K, Smith A 4th, Mahan A, Karim M, Licht A, Zvonar I, Tedesco J, Anderson M, Chapel A, Suscovich T, Malaspina D, Streeck H, Walker BD, Kim A, Lauer G, Altfeld M, Pillai S, Szleifer I, Kelleher NL, Kiser PF, Hope TJ, Alter G. Gunn B, et al. Among authors: chapel a. Mucosal Immunol. 2016 Nov;9(6):1549-1558. doi: 10.1038/mi.2016.8. Epub 2016 Mar 9. Mucosal Immunol. 2016. PMID: 26960182 Free PMC article.
A subset of HLA-DP molecules serve as ligands for the natural cytotoxicity receptor NKp44.
Niehrs A, Garcia-Beltran WF, Norman PJ, Watson GM, Hölzemer A, Chapel A, Richert L, Pommerening-Röser A, Körner C, Ozawa M, Martrus G, Rossjohn J, Lee JH, Berry R, Carrington M, Altfeld M. Niehrs A, et al. Among authors: chapel a. Nat Immunol. 2019 Sep;20(9):1129-1137. doi: 10.1038/s41590-019-0448-4. Epub 2019 Jul 29. Nat Immunol. 2019. PMID: 31358998 Free PMC article.
Dynamics of virological and immunological markers of HIV persistence after allogeneic haematopoietic stem-cell transplantation in the IciStem cohort: a prospective observational cohort study.
Salgado M, Gálvez C, Nijhuis M, Kwon M, Cardozo-Ojeda EF, Badiola J, Gorman MJ, Huyveneers LEP, Urrea V, Bandera A, Jensen BO, Vandekerckhove L, Jurado M, Raj K, Schulze Zur Wiesch J, Bailén R, Eberhard JM, Nabergoj M, Hütter G, Saldaña-Moreno R, Oldford S, Barrett L, Ramirez MLM, Garba S, Gupta RK, Revollo B, Ferra-Coll C, Kuball J, Alter G, Sáez-Cirión A, Diez-Martin JL, Duke ER, Schiffer JT, Wensing A, Martinez-Picado J; IciStem Consortium. Salgado M, et al. Lancet HIV. 2024 Jun;11(6):e389-e405. doi: 10.1016/S2352-3018(24)00090-0. Lancet HIV. 2024. PMID: 38816141
Sustained HIV remission after allogeneic hematopoietic stem cell transplantation with wild-type CCR5 donor cells.
Sáez-Cirión A, Mamez AC, Avettand-Fenoel V, Nabergoj M, Passaes C, Thoueille P, Decosterd L, Hentzien M, Perdomo-Celis F, Salgado M, Nijhuis M, Mélard A, Gardiennet E, Lorin V, Monceaux V, Chapel A, Gourvès M, Lechartier M, Mouquet H, Wensing A, Martinez-Picado J, Yerly S, Rougemont M, Calmy A. Sáez-Cirión A, et al. Among authors: chapel a. Nat Med. 2024 Sep 2. doi: 10.1038/s41591-024-03277-z. Online ahead of print. Nat Med. 2024. PMID: 39222660
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