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Selective inhibition of stemness through EGFR/FOXA2/SOX9 axis reduces pancreatic cancer metastasis.
Kaushik G, Seshacharyulu P, Rauth S, Nallasamy P, Rachagani S, Nimmakayala RK, Vengoji R, Mallya K, Chirravuri-Venkata R, Singh AB, Foster JM, Ly QP, Smith LM, Lele SM, Malafa MP, Jain M, Ponnusamy MP, Batra SK. Kaushik G, et al. Among authors: lele sm. Oncogene. 2021 Jan;40(4):848-862. doi: 10.1038/s41388-020-01564-w. Epub 2020 Dec 7. Oncogene. 2021. PMID: 33288882 Free PMC article.
MUC16 Regulates TSPYL5 for Lung Cancer Cell Growth and Chemoresistance by Suppressing p53.
Lakshmanan I, Salfity S, Seshacharyulu P, Rachagani S, Thomas A, Das S, Majhi PD, Nimmakayala RK, Vengoji R, Lele SM, Ponnusamy MP, Batra SK, Ganti AK. Lakshmanan I, et al. Among authors: lele sm. Clin Cancer Res. 2017 Jul 15;23(14):3906-3917. doi: 10.1158/1078-0432.CCR-16-2530. Epub 2017 Feb 14. Clin Cancer Res. 2017. PMID: 28196872 Free PMC article.
Cigarette Smoke Induces Stem Cell Features of Pancreatic Cancer Cells via PAF1.
Nimmakayala RK, Seshacharyulu P, Lakshmanan I, Rachagani S, Chugh S, Karmakar S, Rauth S, Vengoji R, Atri P, Talmon GA, Lele SM, Smith LM, Thapa I, Bastola D, Ouellette MM, Batra SK, Ponnusamy MP. Nimmakayala RK, et al. Among authors: lele sm. Gastroenterology. 2018 Sep;155(3):892-908.e6. doi: 10.1053/j.gastro.2018.05.041. Epub 2018 Jun 2. Gastroenterology. 2018. PMID: 29864419 Free PMC article.
FDPS cooperates with PTEN loss to promote prostate cancer progression through modulation of small GTPases/AKT axis.
Seshacharyulu P, Rachagani S, Muniyan S, Siddiqui JA, Cruz E, Sharma S, Krishnan R, Killips BJ, Sheinin Y, Lele SM, Smith LM, Talmon GA, Ponnusamy MP, Datta K, Batra SK. Seshacharyulu P, et al. Among authors: lele sm. Oncogene. 2019 Jun;38(26):5265-5280. doi: 10.1038/s41388-019-0791-9. Epub 2019 Mar 26. Oncogene. 2019. PMID: 30914801 Free PMC article.
Metabolic programming of distinct cancer stem cells promotes metastasis of pancreatic ductal adenocarcinoma.
Nimmakayala RK, Leon F, Rachagani S, Rauth S, Nallasamy P, Marimuthu S, Shailendra GK, Chhonker YS, Chugh S, Chirravuri R, Gupta R, Mallya K, Prajapati DR, Lele SM, C Caffrey T, L Grem J, Grandgenett PM, Hollingsworth MA, Murry DJ, Batra SK, Ponnusamy MP. Nimmakayala RK, et al. Among authors: lele sm. Oncogene. 2021 Jan;40(1):215-231. doi: 10.1038/s41388-020-01518-2. Epub 2020 Oct 27. Oncogene. 2021. PMID: 33110235 Free PMC article.
PGC1α-Mediated Metabolic Reprogramming Drives the Stemness of Pancreatic Precursor Lesions.
Nimmakayala RK, Rauth S, Chirravuri Venkata R, Marimuthu S, Nallasamy P, Vengoji R, Lele SM, Rachagani S, Mallya K, Malafa MP, Ponnusamy MP, Batra SK. Nimmakayala RK, et al. Among authors: lele sm. Clin Cancer Res. 2021 Oct 1;27(19):5415-5429. doi: 10.1158/1078-0432.CCR-20-5020. Clin Cancer Res. 2021. PMID: 34172498 Free PMC article.
Pancreatic Tumor Microenvironment Factor Promotes Cancer Stemness via SPP1-CD44 Axis.
Nallasamy P, Nimmakayala RK, Karmakar S, Leon F, Seshacharyulu P, Lakshmanan I, Rachagani S, Mallya K, Zhang C, Ly QP, Myers MS, Josh L, Grabow CE, Gautam SK, Kumar S, Lele SM, Jain M, Batra SK, Ponnusamy MP. Nallasamy P, et al. Among authors: lele sm. Gastroenterology. 2021 Dec;161(6):1998-2013.e7. doi: 10.1053/j.gastro.2021.08.023. Epub 2021 Aug 19. Gastroenterology. 2021. PMID: 34418441 Free PMC article.
140 results