Horn M - Search Results

1

Small-molecule inhibitors of human mitochondrial DNA transcription.

Bonekamp NA, Peter B, Hillen HS, Felser A, Bergbrede T, Choidas A, Horn M, Unger A, Di Lucrezia R, Atanassov I, Li X, Koch U, Menninger S, Boros J, Habenberger P, Giavalisco P, Cramer P, Denzel MS, Nussbaumer P, Klebl B, Falkenberg M, Gustafsson CM, Larsson NG. Bonekamp NA, et al. Among authors: horn m. Nature. 2020 Dec;588(7839):712-716. doi: 10.1038/s41586-020-03048-z. Epub 2020 Dec 16. Nature. 2020. PMID: 33328633

2

Unbiased Forward Genetic Screening with Chemical Mutagenesis to Uncover Drug-Target Interactions.

Horn M, Metge F, Denzel MS. Horn M, et al. Methods Mol Biol. 2019;1953:23-31. doi: 10.1007/978-1-4939-9145-7_2. Methods Mol Biol. 2019. PMID: 30912013

3

Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis.

Ruegenberg S, Horn M, Pichlo C, Allmeroth K, Baumann U, Denzel MS. Ruegenberg S, et al. Among authors: horn m. Nat Commun. 2020 Feb 4;11(1):687. doi: 10.1038/s41467-020-14524-5. Nat Commun. 2020. PMID: 32019926 Free PMC article.

4

Bortezomib resistance mutations in PSMB5 determine response to second-generation proteasome inhibitors in multiple myeloma.

Allmeroth K, Horn M, Kroef V, Miethe S, Müller RU, Denzel MS. Allmeroth K, et al. Among authors: horn m. Leukemia. 2021 Mar;35(3):887-892. doi: 10.1038/s41375-020-0989-4. Epub 2020 Jul 20. Leukemia. 2021. PMID: 32690882 Free PMC article. No abstract available.

5

Unbiased compound-protein interface mapping and prediction of chemoresistance loci through forward genetics in haploid stem cells.

Horn M, Kroef V, Allmeroth K, Schuller N, Miethe S, Peifer M, Penninger JM, Elling U, Denzel MS. Horn M, et al. Oncotarget. 2018 Jan 23;9(11):9838-9851. doi: 10.18632/oncotarget.24305. eCollection 2018 Feb 9. Oncotarget. 2018. PMID: 29515774 Free PMC article.

6

GFPT2/GFAT2 and AMDHD2 act in tandem to control the hexosamine pathway.

Kroef V, Ruegenberg S, Horn M, Allmeroth K, Ebert L, Bozkus S, Miethe S, Elling U, Schermer B, Baumann U, Denzel MS. Kroef V, et al. Among authors: horn m. Elife. 2022 Mar 1;11:e69223. doi: 10.7554/eLife.69223. Elife. 2022. PMID: 35229715 Free PMC article.

7

The E3 ubiquitin ligase UBR5 interacts with the H/ACA ribonucleoprotein complex and regulates ribosomal RNA biogenesis in embryonic stem cells.

Saez I, Gerbracht JV, Koyuncu S, Lee HJ, Horn M, Kroef V, Denzel MS, Dieterich C, Gehring NH, Vilchez D. Saez I, et al. Among authors: horn m. FEBS Lett. 2020 Jan;594(1):175-188. doi: 10.1002/1873-3468.13559. Epub 2019 Aug 8. FEBS Lett. 2020. PMID: 31365120 Free article.

8

Hexosamine Pathway Activation Improves Protein Homeostasis through the Integrated Stress Response.

Horn M, Denzel SI, Srinivasan B, Allmeroth K, Schiffer I, Karthikaisamy V, Miethe S, Breuer P, Antebi A, Denzel MS. Horn M, et al. iScience. 2020 Mar 27;23(3):100887. doi: 10.1016/j.isci.2020.100887. Epub 2020 Feb 5. iScience. 2020. PMID: 32086012 Free PMC article.

9

Human soluble ACE2 improves the effect of remdesivir in SARS-CoV-2 infection.

Monteil V, Dyczynski M, Lauschke VM, Kwon H, Wirnsberger G, Youhanna S, Zhang H, Slutsky AS, Hurtado Del Pozo C, Horn M, Montserrat N, Penninger JM, Mirazimi A. Monteil V, et al. Among authors: horn m. EMBO Mol Med. 2021 Jan 11;13(1):e13426. doi: 10.15252/emmm.202013426. Epub 2020 Dec 14. EMBO Mol Med. 2021. PMID: 33179852 Free PMC article.

10

DRE-1/FBXO11-dependent degradation of BLMP-1/BLIMP-1 governs C. elegans developmental timing and maturation.

Horn M, Geisen C, Cermak L, Becker B, Nakamura S, Klein C, Pagano M, Antebi A. Horn M, et al. Dev Cell. 2014 Mar 31;28(6):697-710. doi: 10.1016/j.devcel.2014.01.028. Epub 2014 Mar 6. Dev Cell. 2014. PMID: 24613396 Free PMC article.

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