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Page 1
Design of novel granulopoietic proteins by topological rescaffolding.
Hernandez Alvarez B, Skokowa J, Coles M, Mir P, Nasri M, Maksymenko K, Weidmann L, Rogers KW, Welte K, Lupas AN, Müller P, ElGamacy M. Hernandez Alvarez B, et al. Among authors: elgamacy m. PLoS Biol. 2020 Dec 22;18(12):e3000919. doi: 10.1371/journal.pbio.3000919. eCollection 2020 Dec. PLoS Biol. 2020. PMID: 33351791 Free PMC article.
A topological refactoring design strategy yields highly stable granulopoietic proteins.
Skokowa J, Hernandez Alvarez B, Coles M, Ritter M, Nasri M, Haaf J, Aghaallaei N, Xu Y, Mir P, Krahl AC, Rogers KW, Maksymenko K, Bajoghli B, Welte K, Lupas AN, Müller P, ElGamacy M. Skokowa J, et al. Among authors: elgamacy m. Nat Commun. 2022 May 26;13(1):2948. doi: 10.1038/s41467-022-30157-2. Nat Commun. 2022. PMID: 35618709 Free PMC article.
The design of functional proteins using tensorized energy calculations.
Maksymenko K, Maurer A, Aghaallaei N, Barry C, Borbarán-Bravo N, Ullrich T, Dijkstra TMH, Hernandez Alvarez B, Müller P, Lupas AN, Skokowa J, ElGamacy M. Maksymenko K, et al. Among authors: elgamacy m. Cell Rep Methods. 2023 Aug 15;3(8):100560. doi: 10.1016/j.crmeth.2023.100560. eCollection 2023 Aug 28. Cell Rep Methods. 2023. PMID: 37671023 Free PMC article.
Accelerating therapeutic protein design.
ElGamacy M. ElGamacy M. Adv Protein Chem Struct Biol. 2022;130:85-118. doi: 10.1016/bs.apcsb.2022.01.004. Epub 2022 Mar 2. Adv Protein Chem Struct Biol. 2022. PMID: 35534117 Review.
15 results