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Computational drug treatment simulations on projections of dysregulated protein networks derived from the myelodysplastic mutanome match clinical response in patients.
Drusbosky L, Medina C, Martuscello R, Hawkins KE, Chang M, Lamba JK, Vali S, Kumar A, Singh NK, Abbasi T, Sekeres MA, Mallo M, Sole F, Bejar R, Cogle CR. Drusbosky L, et al. Among authors: cogle cr. Leuk Res. 2017 Jan;52:1-7. doi: 10.1016/j.leukres.2016.11.004. Epub 2016 Nov 6. Leuk Res. 2017. PMID: 27855285 Free article.
A genomics-informed computational biology platform prospectively predicts treatment responses in AML and MDS patients.
Drusbosky LM, Singh NK, Hawkins KE, Salan C, Turcotte M, Wise EA, Meacham A, Vijay V, Anderson GG, Kim CC, Radhakrishnan S, Ullal Y, Talawdekar A, Sikora H, Nair P, Khanna-Gupta A, Abbasi T, Vali S, Guha S, Farhadfar N, Murthy HS, Horn BN, Leather HL, Castillo P, Tucker C, Cline C, Pettiford L, Lamba JK, Moreb JS, Brown RA, Norkin M, Hiemenz JW, Hsu JW, Slayton WB, Wingard JR, Cogle CR. Drusbosky LM, et al. Among authors: cogle cr. Blood Adv. 2019 Jun 25;3(12):1837-1847. doi: 10.1182/bloodadvances.2018028316. Blood Adv. 2019. PMID: 31208955 Free PMC article. Clinical Trial.
Genome-wide CRISPR/Cas9 screen identifies etoposide response modulators associated with clinical outcomes in pediatric AML.
Nguyen NHK, Rafiee R, Tagmount A, Sobh A, Loguinov A, de Jesus Sosa AK, Elsayed AH, Gbadamosi M, Seligson N, Cogle CR, Rubnitz J, Ribeiro R, Downing J, Cao X, Pounds SB, Vulpe CD, Lamba JK. Nguyen NHK, et al. Among authors: cogle cr. Blood Adv. 2023 May 9;7(9):1769-1783. doi: 10.1182/bloodadvances.2022007934. Blood Adv. 2023. PMID: 36111891 Free PMC article.
Leukemia regression by vascular disruption and antiangiogenic therapy.
Madlambayan GJ, Meacham AM, Hosaka K, Mir S, Jorgensen M, Scott EW, Siemann DW, Cogle CR. Madlambayan GJ, et al. Among authors: cogle cr. Blood. 2010 Sep 2;116(9):1539-47. doi: 10.1182/blood-2009-06-230474. Epub 2010 May 14. Blood. 2010. PMID: 20472832 Free PMC article.
146 results