Mandikian D - Search Results

1

Preclinical optimization of Ly6E-targeted ADCs for increased durability and efficacy of anti-tumor response.

Dela Cruz Chuh J, Go M, Chen Y, Guo J, Rafidi H, Mandikian D, Sun Y, Lin Z, Schneider K, Zhang P, Vij R, Sharpnack D, Chan P, de la Cruz C, Sadowsky J, Seshasayee D, Koerber JT, Pillow TH, Phillips GD, Rowntree RK, Boswell CA, Kozak KR, Polson AG, Polakis P, Yu SF, Dragovich PS, Agard NJ. Dela Cruz Chuh J, et al. Among authors: mandikian d. MAbs. 2021 Jan-Dec;13(1):1862452. doi: 10.1080/19420862.2020.1862452. MAbs. 2021. PMID: 33382956 Free PMC article.

2

Preclinical pharmacokinetic characterization of an adipose tissue-targeting monoclonal antibody in obese and non-obese animals.

Rajan S, Mandikian D, Baruch A, Gelzleichter TR, Stevens D, Sonoda J, Cowan K, Boswell CA, Stefanich E. Rajan S, et al. Among authors: mandikian d. MAbs. 2017 Nov/Dec;9(8):1379-1388. doi: 10.1080/19420862.2017.1373923. Epub 2017 Sep 12. MAbs. 2017. PMID: 28895785 Free PMC article.

3

Relative Target Affinities of T-Cell-Dependent Bispecific Antibodies Determine Biodistribution in a Solid Tumor Mouse Model.

Mandikian D, Takahashi N, Lo AA, Li J, Eastham-Anderson J, Slaga D, Ho J, Hristopoulos M, Clark R, Totpal K, Lin K, Joseph SB, Dennis MS, Prabhu S, Junttila TT, Boswell CA. Mandikian D, et al. Mol Cancer Ther. 2018 Apr;17(4):776-785. doi: 10.1158/1535-7163.MCT-17-0657. Epub 2018 Jan 16. Mol Cancer Ther. 2018. PMID: 29339550

4

Antibody-mediated stabilization of NRG1 induces behavioral and electrophysiological alterations in adult mice.

Dominguez SL, Hegde GV, Hanson JE, Xiang H, Mandikian D, Boswell CA, Chiu C, Wu Y, Tsai SP, Fleck D, Weber M, Ngu H, Scearce-Levie K, Jackson EL. Dominguez SL, et al. Among authors: mandikian d. Sci Rep. 2018 May 29;8(1):8239. doi: 10.1038/s41598-018-26492-4. Sci Rep. 2018. PMID: 29844389 Free PMC article.

5

Site-specific conjugation allows modulation of click reaction stoichiometry for pretargeted SPECT imaging.

Mandikian D, Rafidi H, Adhikari P, Venkatraman P, Nazarova L, Fung G, Figueroa I, Ferl GZ, Ulufatu S, Ho J, McCaughey C, Lau J, Yu SF, Prabhu S, Sadowsky J, Boswell CA. Mandikian D, et al. MAbs. 2018 Nov-Dec;10(8):1269-1280. doi: 10.1080/19420862.2018.1521132. Epub 2018 Oct 4. MAbs. 2018. PMID: 30199303 Free PMC article.

6

Tissue Physiology of Cynomolgus Monkeys: Cross-Species Comparison and Implications for Translational Pharmacology.

Mandikian D, Figueroa I, Oldendorp A, Rafidi H, Ulufatu S, Schweiger MG, Couch JA, Dybdal N, Joseph SB, Prabhu S, Ferl GZ, Boswell CA. Mandikian D, et al. AAPS J. 2018 Oct 8;20(6):107. doi: 10.1208/s12248-018-0264-z. AAPS J. 2018. PMID: 30298434

7

Production, characterization, and in vivo half-life extension of polymeric IgA molecules in mice.

Lombana TN, Rajan S, Zorn JA, Mandikian D, Chen EC, Estevez A, Yip V, Bravo DD, Phung W, Farahi F, Viajar S, Lee S, Gill A, Sandoval W, Wang J, Ciferri C, Boswell CA, Matsumoto ML, Spiess C. Lombana TN, et al. Among authors: mandikian d. MAbs. 2019 Aug/Sep;11(6):1122-1138. doi: 10.1080/19420862.2019.1622940. Epub 2019 Jun 9. MAbs. 2019. PMID: 31122132 Free PMC article.

8

Effect of Modulating FcRn Binding on Direct and Pretargeted Tumor Uptake of Full-length Antibodies.

Nazarova L, Rafidi H, Mandikian D, Ferl GZ, Koerber JT, Davies CW, Ulufatu S, Ho J, Lau J, Yu SF, Ernst J, Sadowsky JD, Boswell CA. Nazarova L, et al. Among authors: mandikian d. Mol Cancer Ther. 2020 Apr;19(4):1052-1058. doi: 10.1158/1535-7163.MCT-19-1015. Epub 2020 Feb 5. Mol Cancer Ther. 2020. PMID: 32024685

9

Anti-LYPD1/CD3 T-Cell-Dependent Bispecific Antibody for the Treatment of Ovarian Cancer.

Lo AA, Johnston J, Li J, Mandikian D, Hristopoulos M, Clark R, Nickles D, Liang WC, Hötzel K, Dunlap D, Pham T, Cai H, Ovacik M, Bravo-Perez D, Mai E, Slaga D, Ellerman D, Ziai J, Totpal K, Lee G, Boswell CA, Payandeh J, Wu Y, Junttila TT. Lo AA, et al. Among authors: mandikian d. Mol Cancer Ther. 2021 Apr;20(4):716-725. doi: 10.1158/1535-7163.MCT-20-0490. Epub 2021 Feb 3. Mol Cancer Ther. 2021. PMID: 33536191

10

Valency of HER2 Targeting Antibodies Influences Tumor Cell Internalization and Penetration.

Ramos MK, Mandikian D, Sermeño LN, King A, Dent AT, Ho J, Ulufatu S, Lombana TN, Spiess C, Go MAT, Yu SF, Kamath AV, Ferl GZ, Boswell CA. Ramos MK, et al. Among authors: mandikian d. Mol Cancer Ther. 2021 Oct;20(10):1956-1965. doi: 10.1158/1535-7163.MCT-20-1097. Epub 2021 Jul 12. Mol Cancer Ther. 2021. PMID: 34253591

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