Pintzas A - Search Results

1

BRAF paradox breakers PLX8394, PLX7904 are more effective against BRAFV600Ε CRC cells compared with the BRAF inhibitor PLX4720 and shown by detailed pathway analysis.

Koumaki K, Kontogianni G, Kosmidou V, Pahitsa F, Kritsi E, Zervou M, Chatziioannou A, Souliotis VL, Papadodima O, Pintzas A. Koumaki K, et al. Among authors: pintzas a. Biochim Biophys Acta Mol Basis Dis. 2021 Apr 1;1867(4):166061. doi: 10.1016/j.bbadis.2020.166061. Epub 2020 Dec 29. Biochim Biophys Acta Mol Basis Dis. 2021. PMID: 33385518 Free article.

2

Tumor heterogeneity revealed by KRAS, BRAF, and PIK3CA pyrosequencing: KRAS and PIK3CA intratumor mutation profile differences and their therapeutic implications.

Kosmidou V, Oikonomou E, Vlassi M, Avlonitis S, Katseli A, Tsipras I, Mourtzoukou D, Kontogeorgos G, Zografos G, Pintzas A. Kosmidou V, et al. Among authors: pintzas a. Hum Mutat. 2014 Mar;35(3):329-40. doi: 10.1002/humu.22496. Epub 2014 Jan 15. Hum Mutat. 2014. PMID: 24352906

3

TRAIL receptor upregulation and the implication of KRAS/BRAF mutations in human colon cancer tumors.

Oikonomou E, Kosmidou V, Katseli A, Kothonidis K, Mourtzoukou D, Kontogeorgos G, Andera L, Zografos G, Pintzas A. Oikonomou E, et al. Among authors: pintzas a. Int J Cancer. 2009 Nov 1;125(9):2127-35. doi: 10.1002/ijc.24613. Int J Cancer. 2009. PMID: 19637313

4

Death receptor 5 (DR5) and a 5-gene apoptotic biomarker panel with significant differential diagnostic potential in colorectal cancer.

Devetzi M, Kosmidou V, Vlassi M, Perysinakis I, Aggeli C, Choreftaki T, Zografos GN, Pintzas A. Devetzi M, et al. Among authors: pintzas a. Sci Rep. 2016 Nov 9;6:36532. doi: 10.1038/srep36532. Sci Rep. 2016. PMID: 27827395 Free PMC article.

5

EZH2 is regulated by ERK/AKT and targets integrin alpha2 gene to control Epithelial-Mesenchymal Transition and anoikis in colon cancer cells.

Ferraro A, Mourtzoukou D, Kosmidou V, Avlonitis S, Kontogeorgos G, Zografos G, Pintzas A. Ferraro A, et al. Among authors: pintzas a. Int J Biochem Cell Biol. 2013 Feb;45(2):243-54. doi: 10.1016/j.biocel.2012.10.009. Epub 2012 Oct 30. Int J Biochem Cell Biol. 2013. PMID: 23116973

6

Epigenetic regulation of miR-21 in colorectal cancer: ITGB4 as a novel miR-21 target and a three-gene network (miR-21-ITGΒ4-PDCD4) as predictor of metastatic tumor potential.

Ferraro A, Kontos CK, Boni T, Bantounas I, Siakouli D, Kosmidou V, Vlassi M, Spyridakis Y, Tsipras I, Zografos G, Pintzas A. Ferraro A, et al. Among authors: pintzas a. Epigenetics. 2014 Jan;9(1):129-41. doi: 10.4161/epi.26842. Epub 2013 Oct 22. Epigenetics. 2014. PMID: 24149370 Free PMC article.

7

Noxa upregulation and 5-gene apoptotic biomarker panel in colorectal cancer.

Kosmidou V, Vlassi M, Anagiotos K, Raftopoulou S, Kalogerakou E, Skarmalioraki S, Aggeli C, Choreftaki T, Zografos G, Pintzas A. Kosmidou V, et al. Among authors: pintzas a. Eur J Clin Invest. 2021 Jan;51(1):e13353. doi: 10.1111/eci.13353. Epub 2020 Aug 11. Eur J Clin Invest. 2021. PMID: 32682341

8

BRAF vs RAS oncogenes: are mutations of the same pathway equal? Differential signalling and therapeutic implications.

Oikonomou E, Koustas E, Goulielmaki M, Pintzas A. Oikonomou E, et al. Among authors: pintzas a. Oncotarget. 2014 Dec 15;5(23):11752-77. doi: 10.18632/oncotarget.2555. Oncotarget. 2014. PMID: 25361007 Free PMC article. Review.

9

BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells.

Goulielmaki M, Koustas E, Moysidou E, Vlassi M, Sasazuki T, Shirasawa S, Zografos G, Oikonomou E, Pintzas A. Goulielmaki M, et al. Among authors: pintzas a. Oncotarget. 2016 Feb 23;7(8):9188-221. doi: 10.18632/oncotarget.6942. Oncotarget. 2016. PMID: 26802026 Free PMC article.

10

IAP antagonists Birinapant and AT-406 efficiently synergise with either TRAIL, BRAF, or BCL-2 inhibitors to sensitise BRAFV600E colorectal tumour cells to apoptosis.

Perimenis P, Galaris A, Voulgari A, Prassa M, Pintzas A. Perimenis P, et al. Among authors: pintzas a. BMC Cancer. 2016 Aug 12;16:624. doi: 10.1186/s12885-016-2606-5. BMC Cancer. 2016. PMID: 27520705 Free PMC article.

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