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Relieving DYRK1A repression of MKL1 confers an adult-like phenotype to human infantile megakaryocytes.
Elagib KE, Brock A, Clementelli CM, Mosoyan G, Delehanty LL, Sahu RK, Pacheco-Benichou A, Fruit C, Besson T, Morris SW, Eto K, Jobaliya C, French DL, Gadue P, Singh S, Shi X, Qin F, Cornelison R, Li H, Iancu-Rubin C, Goldfarb AN. Elagib KE, et al. Among authors: pacheco benichou a. J Clin Invest. 2022 Oct 3;132(19):e154839. doi: 10.1172/JCI154839. J Clin Invest. 2022. PMID: 35925681 Free PMC article.
DYRK1A regulates B cell acute lymphoblastic leukemia through phosphorylation of FOXO1 and STAT3.
Bhansali RS, Rammohan M, Lee P, Laurent AP, Wen Q, Suraneni P, Yip BH, Tsai YC, Jenni S, Bornhauser B, Siret A, Fruit C, Pacheco-Benichou A, Harris E, Besson T, Thompson BJ, Goo YA, Hijiya N, Vilenchik M, Izraeli S, Bourquin JP, Malinge S, Crispino JD. Bhansali RS, et al. Among authors: pacheco benichou a. J Clin Invest. 2021 Jan 4;131(1):e135937. doi: 10.1172/JCI135937. J Clin Invest. 2021. PMID: 33393494 Free PMC article.