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Page 1
Discovery of an Allosteric Ligand Binding Site in SMYD3 Lysine Methyltransferase.
Talibov VO, Fabini E, FitzGerald EA, Tedesco D, Cederfeldt D, Talu MJ, Rachman MM, Mihalic F, Manoni E, Naldi M, Sanese P, Forte G, Lepore Signorile M, Barril X, Simone C, Bartolini M, Dobritzsch D, Del Rio A, Danielson UH. Talibov VO, et al. Chembiochem. 2021 May 4;22(9):1597-1608. doi: 10.1002/cbic.202000736. Epub 2021 Feb 11. Chembiochem. 2021. PMID: 33400854 Free PMC article.
Proximity-dependent initiation of hybridization chain reaction.
Koos B, Cane G, Grannas K, Löf L, Arngården L, Heldin J, Clausson CM, Klaesson A, Hirvonen MK, de Oliveira FM, Talibov VO, Pham NT, Auer M, Danielson UH, Haybaeck J, Kamali-Moghaddam M, Söderberg O. Koos B, et al. Among authors: talibov vo. Nat Commun. 2015 Jun 12;6:7294. doi: 10.1038/ncomms8294. Nat Commun. 2015. PMID: 26065580 Free PMC article.
Unveiling the Biochemistry of the Epigenetic Regulator SMYD3.
Fabini E, Talibov VO, Mihalic F, Naldi M, Bartolini M, Bertucci C, Del Rio A, Danielson UH. Fabini E, et al. Among authors: talibov vo. Biochemistry. 2019 Sep 3;58(35):3634-3645. doi: 10.1021/acs.biochem.9b00420. Epub 2019 Aug 21. Biochemistry. 2019. PMID: 31389685
Macrocyclic Peptides Uncover a Novel Binding Mode for Reversible Inhibitors of LSD1.
Yang J, Talibov VO, Peintner S, Rhee C, Poongavanam V, Geitmann M, Sebastiano MR, Simon B, Hennig J, Dobritzsch D, Danielson UH, Kihlberg J. Yang J, et al. Among authors: talibov vo. ACS Omega. 2020 Feb 17;5(8):3979-3995. doi: 10.1021/acsomega.9b03493. eCollection 2020 Mar 3. ACS Omega. 2020. PMID: 32149225 Free PMC article.
Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses.
Luttens A, Gullberg H, Abdurakhmanov E, Vo DD, Akaberi D, Talibov VO, Nekhotiaeva N, Vangeel L, De Jonghe S, Jochmans D, Krambrich J, Tas A, Lundgren B, Gravenfors Y, Craig AJ, Atilaw Y, Sandström A, Moodie LWK, Lundkvist Å, van Hemert MJ, Neyts J, Lennerstrand J, Kihlberg J, Sandberg K, Danielson UH, Carlsson J. Luttens A, et al. Among authors: talibov vo. J Am Chem Soc. 2022 Feb 23;144(7):2905-2920. doi: 10.1021/jacs.1c08402. Epub 2022 Feb 10. J Am Chem Soc. 2022. PMID: 35142215 Free PMC article.
Discovery of the 4-aminopiperidine-based compound EM127 for the site-specific covalent inhibition of SMYD3.
Parenti MD, Naldi M, Manoni E, Fabini E, Cederfelt D, Talibov VO, Gressani V, Guven U, Grossi V, Fasano C, Sanese P, De Marco K, Shtil AA, Kurkin AV, Altieri A, Danielson UH, Caretti G, Simone C, Varchi G, Bartolini M, Del Rio A. Parenti MD, et al. Among authors: talibov vo. Eur J Med Chem. 2022 Dec 5;243:114683. doi: 10.1016/j.ejmech.2022.114683. Epub 2022 Sep 8. Eur J Med Chem. 2022. PMID: 36116234
Multiplexed experimental strategies for fragment library screening against challenging drug targets using SPR biosensors.
FitzGerald EA, Vagrys D, Opassi G, Klein HF, Hamilton DJ, Talibov VO, Abramsson M, Moberg A, Lindgren MT, Holmgren C, Davis B, O'Brien P, Wijtmans M, Hubbard RE, de Esch IJP, Danielson UH. FitzGerald EA, et al. Among authors: talibov vo. SLAS Discov. 2024 Jan;29(1):40-51. doi: 10.1016/j.slasd.2023.09.001. Epub 2023 Sep 14. SLAS Discov. 2024. PMID: 37714432 Free article.
18 results