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Autophagy impairment as a key feature for acetaminophen-induced ototoxicity.
Zhao T, Zheng T, Yu H, Hu BH, Hu B, Ma P, Yang Y, Yang N, Hu J, Cao T, Chen G, Yan B, Peshoff M, Hatzoglou M, Geng R, Li B, Zheng QY. Zhao T, et al. Among authors: hatzoglou m. Cell Death Dis. 2021 Jan 4;12(1):3. doi: 10.1038/s41419-020-03328-6. Cell Death Dis. 2021. PMID: 33414397 Free PMC article.
Tumor suppressor mediated ubiquitylation of hnRNPK is a barrier to oncogenic translation.
Mucha B, Qie S, Bajpai S, Tarallo V, Diehl JN, Tedeschi F, Zhou G, Gao Z, Flashner S, Klein-Szanto AJ, Hibshoosh H, Masataka S, Chajewski OS, Majsterek I, Pytel D, Hatzoglou M, Der CJ, Nakagawa H, Bass AJ, Wong KK, Fuchs SY, Rustgi AK, Jankowsky E, Diehl JA. Mucha B, et al. Among authors: hatzoglou m. Nat Commun. 2022 Nov 3;13(1):6614. doi: 10.1038/s41467-022-34402-6. Nat Commun. 2022. PMID: 36329064 Free PMC article.
Downregulation of PERK activity and eIF2α serine 51 phosphorylation by mTOR complex 1 elicits pro-oxidant and pro-death effects in tuberous sclerosis-deficient cells.
Krishnamoorthy J, Tenkerian C, Gupta J, Ghaddar N, Wang S, Darini C, Staschke KA, Ghosh A, Gandin V, Topisirovic I, Kristof AS, Hatzoglou M, Simos G, Koromilas AE. Krishnamoorthy J, et al. Among authors: hatzoglou m. Cell Death Dis. 2018 Feb 15;9(3):254. doi: 10.1038/s41419-018-0326-2. Cell Death Dis. 2018. PMID: 29449538 Free PMC article.
Role of Endoplasmic Reticulum Stress in Otitis Media.
Zhao H, Wang Y, Li B, Zheng T, Liu X, Hu BH, Che J, Zhao T, Chen J, Hatzoglou M, Zhang X, Fan Z, Zheng Q. Zhao H, et al. Among authors: hatzoglou m. Front Genet. 2020 May 27;11:495. doi: 10.3389/fgene.2020.00495. eCollection 2020. Front Genet. 2020. PMID: 32536938 Free PMC article.
A self-defeating anabolic program leads to β-cell apoptosis in endoplasmic reticulum stress-induced diabetes via regulation of amino acid flux.
Krokowski D, Han J, Saikia M, Majumder M, Yuan CL, Guan BJ, Bevilacqua E, Bussolati O, Bröer S, Arvan P, Tchórzewski M, Snider MD, Puchowicz M, Croniger CM, Kimball SR, Pan T, Koromilas AE, Kaufman RJ, Hatzoglou M. Krokowski D, et al. Among authors: hatzoglou m. J Biol Chem. 2013 Jun 14;288(24):17202-13. doi: 10.1074/jbc.M113.466920. Epub 2013 May 3. J Biol Chem. 2013. PMID: 23645676 Free PMC article.
126 results