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Comparable frequency of BRCA1, BRCA2 and TP53 germline mutations in a multi-ethnic Asian cohort suggests TP53 screening should be offered together with BRCA1/2 screening to early-onset breast cancer patients.
Lee DS, Yoon SY, Looi LM, Kang P, Kang IN, Sivanandan K, Ariffin H, Thong MK, Chin KF, Mohd Taib NA, Yip CH, Teo SH. Lee DS, et al. Among authors: yip ch. Breast Cancer Res. 2012 Apr 16;14(2):R66. doi: 10.1186/bcr3172. Breast Cancer Res. 2012. PMID: 22507745 Free PMC article.
Triple-negative breast cancer and PTEN (phosphatase and tensin homologue) loss are predictors of BRCA1 germline mutations in women with early-onset and familial breast cancer, but not in women with isolated late-onset breast cancer.
Phuah SY, Looi LM, Hassan N, Rhodes A, Dean S, Taib NA, Yip CH, Teo SH. Phuah SY, et al. Among authors: yip ch. Breast Cancer Res. 2012 Nov 2;14(6):R142. doi: 10.1186/bcr3347. Breast Cancer Res. 2012. PMID: 23116406 Free PMC article.
289 results