Chang L - Search Results

1

New designed pH-responsive histidine-rich peptides with antitumor activity.

Chang L, Bao H, Yao J, Liu H, Gou S, Zhong C, Zhang Y, Ni J. Chang L, et al. J Drug Target. 2021 Jul;29(6):651-659. doi: 10.1080/1061186X.2021.1873351. Epub 2021 Jan 19. J Drug Target. 2021. PMID: 33428507

2

Design of a new pH-activatable cell-penetrating peptide for drug delivery into tumor cells.

Zhang Y, Li L, Chang L, Liu H, Song J, Liu Y, Bao H, Liu B, Wang R, Ni J. Zhang Y, et al. Among authors: chang l. Chem Biol Drug Des. 2019 Sep;94(5):1884-1893. doi: 10.1111/cbdd.13537. Epub 2019 Sep 25. Chem Biol Drug Des. 2019. PMID: 31062442

3

Effect of N-methylated and fatty acid conjugation on analogs of antimicrobial peptide Anoplin.

Liu T, Zhu N, Zhong C, Zhu Y, Gou S, Chang L, Bao H, Liu H, Zhang Y, Ni J. Liu T, et al. Among authors: chang l. Eur J Pharm Sci. 2020 Sep 1;152:105453. doi: 10.1016/j.ejps.2020.105453. Epub 2020 Jul 7. Eur J Pharm Sci. 2020. PMID: 32649983

4

Novel Broad-Spectrum Antimicrobial Peptide Derived from Anoplin and Its Activity on Bacterial Pneumonia in Mice.

Gou S, Li B, Ouyang X, Ba Z, Zhong C, Zhang T, Chang L, Zhu Y, Zhang J, Zhu N, Zhang Y, Liu H, Ni J. Gou S, et al. Among authors: chang l. J Med Chem. 2021 Aug 12;64(15):11247-11266. doi: 10.1021/acs.jmedchem.1c00614. Epub 2021 Jun 28. J Med Chem. 2021. PMID: 34180670

5

Novel synovial targeting peptide-sinomenine conjugates as a potential strategy for the treatment of rheumatoid arthritis.

Zhang T, Ouyang X, Gou S, Zhang Y, Yan N, Chang L, Li B, Zhang F, Liu H, Ni J. Zhang T, et al. Among authors: chang l. Int J Pharm. 2022 Apr 5;617:121628. doi: 10.1016/j.ijpharm.2022.121628. Epub 2022 Mar 1. Int J Pharm. 2022. PMID: 35245636

6

Constructing new acid-activated anticancer peptide by attaching a desirable anionic binding partner peptide.

Zhang Y, Chang L, Bao H, Wu X, Liu H, Gou S, Zhang J, Ni J. Zhang Y, et al. Among authors: chang l. J Drug Target. 2022 Nov;30(9):973-982. doi: 10.1080/1061186X.2022.2070627. Epub 2022 Jun 2. J Drug Target. 2022. PMID: 35502656

7

Improving the Antimicrobial Performance of Amphiphilic Cationic Antimicrobial Peptides Using Glutamic Acid Full-Scan and Positive Charge Compensation Strategies.

Ouyang X, Li B, Yang Y, Ba Z, Zhang J, Zhang T, Chang L, Zhang F, Zhang Y, Liu H, Gou S, Ni J. Ouyang X, et al. Among authors: chang l. J Med Chem. 2022 Oct 27;65(20):13833-13851. doi: 10.1021/acs.jmedchem.2c01076. Epub 2022 Sep 23. J Med Chem. 2022. PMID: 36148510

8

Short, mirror-symmetric antimicrobial peptides centered on "RRR" have broad-spectrum antibacterial activity with low drug resistance and toxicity.

Zhang F, Yang P, Mao W, Zhong C, Zhang J, Chang L, Wu X, Liu H, Zhang Y, Gou S, Ni J. Zhang F, et al. Among authors: chang l. Acta Biomater. 2022 Dec;154:145-167. doi: 10.1016/j.actbio.2022.10.003. Epub 2022 Oct 12. Acta Biomater. 2022. PMID: 36241015

9

One New Acid-Activated Hybrid Anticancer Peptide by Coupling with a Desirable pH-Sensitive Anionic Partner Peptide.

Chang L, Wu X, Ran K, Tian Y, Ouyang X, Liu H, Gou S, Zhang Y, Ni J. Chang L, et al. ACS Omega. 2023 Feb 20;8(8):7536-7545. doi: 10.1021/acsomega.2c06766. eCollection 2023 Feb 28. ACS Omega. 2023. PMID: 36873017 Free PMC article.

10

Structure-Activity Relationship Study of Antimicrobial Peptide PE2 Delivered Novel Linear Derivatives with Potential of Eradicating Biofilms and Low Incidence of Drug Resistance.

Zhang J, Ouyang X, Zhang F, Li B, Chang L, Yang P, Mao W, Gou S, Zhang Y, Liu H, Yao J, Ni J. Zhang J, et al. Among authors: chang l. J Med Chem. 2023 Jul 13;66(13):8526-8544. doi: 10.1021/acs.jmedchem.3c00181. Epub 2023 Jun 27. J Med Chem. 2023. PMID: 37368962

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