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Exome-wide evaluation of rare coding variants using electronic health records identifies new gene-phenotype associations.
Park J, Lucas AM, Zhang X, Chaudhary K, Cho JH, Nadkarni G, Dobbyn A, Chittoor G, Josyula NS, Katz N, Breeyear JH, Ahmadmehrabi S, Drivas TG, Chavali VRM, Fasolino M, Sawada H, Daugherty A, Li Y, Zhang C, Bradford Y, Weaver J, Verma A, Judy RL, Kember RL, Overton JD, Reid JG, Ferreira MAR, Li AH, Baras A, LeMaire SA, Shen YH, Naji A, Kaestner KH, Vahedi G, Edwards TL, Chen J, Damrauer SM, Justice AE, Do R, Ritchie MD, Rader DJ. Park J, et al. Among authors: kember rl. Nat Med. 2021 Jan;27(1):66-72. doi: 10.1038/s41591-020-1133-8. Epub 2021 Jan 11. Nat Med. 2021. PMID: 33432171 Free PMC article.
High dimensional predictions of suicide risk in 4.2 million US Veterans using ensemble transfer learning.
Dhaubhadel S, Ganguly K, Ribeiro RM, Cohn JD, Hyman JM, Hengartner NW, Kolade B, Singley A, Bhattacharya T, Finley P, Levin D, Thelen H, Cho K, Costa L, Ho YL, Justice AC, Pestian J, Santel D, Zamora-Resendiz R, Crivelli S, Tamang S, Martins S, Trafton J, Oslin DW, Beckham JC, Kimbrel NA; Million Veteran Program Suicide Exemplar Work Group; McMahon BH. Dhaubhadel S, et al. Sci Rep. 2024 Jan 20;14(1):1793. doi: 10.1038/s41598-024-51762-9. Sci Rep. 2024. PMID: 38245528 Free PMC article.
Adverse Childhood Events, Mood and Anxiety Disorders, and Substance Dependence: Gene X Environment Effects and Moderated Mediation.
Kranzler HR, Davis CN, Feinn R, Jinwala Z, Khan Y, Oikonomou A, Silva-Lopez D, Burton I, Dixon M, Milone J, Ramirez S, Shifman N, Levey D, Gelernter J, Hartwell EE, Kember RL. Kranzler HR, et al. Among authors: kember rl. medRxiv [Preprint]. 2023 Oct 25:2023.10.24.23297419. doi: 10.1101/2023.10.24.23297419. medRxiv. 2023. Update in: Nat Hum Behav. 2024 Aug;8(8):1616-1627. doi: 10.1038/s41562-024-01885-w PMID: 37961309 Free PMC article. Updated. Preprint.
Genetic contribution to the comorbidity between attention-deficit/hyperactivity disorder and substance use disorders.
Koller D, Mitjans M, Kouakou M, Friligkou E, Cabrera-Mendoza B, Deak JD, Llonga N, Pathak GA, Stiltner B, Løkhammer S, Levey DF, Zhou H, Hatoum AS, Kember RL, Kranzler HR, Stein MB, Corominas R, Demontis D, Artigas MS, Ramos-Quiroga JA, Gelernter J, Ribasés M, Cormand B, Polimanti R. Koller D, et al. Among authors: kember rl. Psychiatry Res. 2024 Mar;333:115758. doi: 10.1016/j.psychres.2024.115758. Epub 2024 Feb 3. Psychiatry Res. 2024. PMID: 38335780 Free article.
A single-nucleus transcriptomic atlas of medium spiny neurons in the rat nucleus accumbens.
Reiner BC, Chehimi SN, Merkel R, Toikumo S, Berrettini WH, Kranzler HR, Sanchez-Roige S, Kember RL, Schmidt HD, Crist RC. Reiner BC, et al. Among authors: kember rl. bioRxiv [Preprint]. 2024 May 26:2024.05.26.595949. doi: 10.1101/2024.05.26.595949. bioRxiv. 2024. Update in: Sci Rep. 2024 Aug 6;14(1):18258. doi: 10.1038/s41598-024-69255-0 PMID: 38826289 Free PMC article. Updated. Preprint.
Application of polygenic scores to a deeply phenotyped sample enriched for substance use disorders reveals extensive pleiotropy with psychiatric and medical traits.
Hartwell EE, Jinwala Z, Milone J, Ramirez S, Gelernter J, Kranzler HR, Kember RL. Hartwell EE, et al. Among authors: kember rl. medRxiv [Preprint]. 2024 Jan 23:2024.01.22.24301615. doi: 10.1101/2024.01.22.24301615. medRxiv. 2024. Update in: Neuropsychopharmacology. 2024 Dec;49(13):1958-1967. doi: 10.1038/s41386-024-01922-2 PMID: 38343859 Free PMC article. Updated. Preprint.
Racial and Ethnic Bias in the Diagnosis of Alcohol Use Disorder in Veterans.
Vickers-Smith R, Justice AC, Becker WC, Rentsch CT, Curtis B, Fernander A, Hartwell EE, Ighodaro ET, Kember RL, Tate J, Kranzler HR. Vickers-Smith R, et al. Among authors: kember rl. Am J Psychiatry. 2023 Jun 1;180(6):426-436. doi: 10.1176/appi.ajp.21111097. Epub 2023 May 3. Am J Psychiatry. 2023. PMID: 37132202 Free PMC article.
111 results