Down-regulation of chondroitin 4-O-sulfotransferase-1 by Wnt signaling triggers diffusion of Wnt-3a.
Nadanaka S, Kinouchi H, Taniguchi-Morita K, Tamura J, Kitagawa H.
Nadanaka S, et al. Among authors: kitagawa h.
J Biol Chem. 2011 Feb 11;286(6):4199-208. doi: 10.1074/jbc.M110.155093. Epub 2010 Dec 1.
J Biol Chem. 2011.
PMID: 21123170
Free PMC article.
The specific chondroitin sulfate (CS) structure synthesized by chondroitin-4-O-sulfotransferase-1 (C4ST-1) binds to Wnt-3a with high affinity (Nadanaka, S., Ishida, M., Ikegami, M., and Kitagawa, H. (2008) J. Biol. Chem. 283, 27333-27343). In this study we tested wh …
The specific chondroitin sulfate (CS) structure synthesized by chondroitin-4-O-sulfotransferase-1 (C4ST-1) binds to Wnt-3a with high affinit …