Lai JR - Search Results

1

Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis.

Herrera NG, Morano NC, Celikgil A, Georgiev GI, Malonis RJ, Lee JH, Tong K, Vergnolle O, Massimi AB, Yen LY, Noble AJ, Kopylov M, Bonanno JB, Garrett-Thomson SC, Hayes DB, Bortz RH 3rd, Wirchnianski AS, Florez C, Laudermilch E, Haslwanter D, Fels JM, Dieterle ME, Jangra RK, Barnhill J, Mengotto A, Kimmel D, Daily JP, Pirofski LA, Chandran K, Brenowitz M, Garforth SJ, Eng ET, Lai JR, Almo SC. Herrera NG, et al. Among authors: lai jr. ACS Omega. 2020 Dec 21;6(1):85-102. doi: 10.1021/acsomega.0c03512. eCollection 2021 Jan 12. ACS Omega. 2020. PMID: 33458462 Free PMC article.

2

Inhibition of Ebola virus entry by a C-peptide targeted to endosomes.

Miller EH, Harrison JS, Radoshitzky SR, Higgins CD, Chi X, Dong L, Kuhn JH, Bavari S, Lai JR, Chandran K. Miller EH, et al. Among authors: lai jr. J Biol Chem. 2011 May 6;286(18):15854-61. doi: 10.1074/jbc.M110.207084. Epub 2011 Mar 16. J Biol Chem. 2011. PMID: 21454542 Free PMC article.

3

Designed protein mimics of the Ebola virus glycoprotein GP2 α-helical bundle: stability and pH effects.

Harrison JS, Higgins CD, Chandran K, Lai JR. Harrison JS, et al. Among authors: lai jr. Protein Sci. 2011 Sep;20(9):1587-96. doi: 10.1002/pro.688. Epub 2011 Aug 3. Protein Sci. 2011. PMID: 21739501 Free PMC article.

4

Marburg virus glycoprotein GP2: pH-dependent stability of the ectodomain α-helical bundle.

Harrison JS, Koellhoffer JF, Chandran K, Lai JR. Harrison JS, et al. Among authors: lai jr. Biochemistry. 2012 Mar 27;51(12):2515-25. doi: 10.1021/bi3000353. Epub 2012 Mar 12. Biochemistry. 2012. PMID: 22369502 Free PMC article.

5

Crystal structure of the Marburg virus GP2 core domain in its postfusion conformation.

Koellhoffer JF, Malashkevich VN, Harrison JS, Toro R, Bhosle RC, Chandran K, Almo SC, Lai JR. Koellhoffer JF, et al. Among authors: lai jr. Biochemistry. 2012 Oct 2;51(39):7665-75. doi: 10.1021/bi300976m. Epub 2012 Sep 19. Biochemistry. 2012. PMID: 22935026 Free PMC article.

6

Two synthetic antibodies that recognize and neutralize distinct proteolytic forms of the ebola virus envelope glycoprotein.

Koellhoffer JF, Chen G, Sandesara RG, Bale S, Saphire EO, Chandran K, Sidhu SS, Lai JR. Koellhoffer JF, et al. Among authors: lai jr. Chembiochem. 2012 Nov 26;13(17):2549-57. doi: 10.1002/cbic.201200493. Epub 2012 Oct 30. Chembiochem. 2012. PMID: 23111988 Free PMC article.

7

Conformational properties of peptides corresponding to the ebolavirus GP2 membrane-proximal external region in the presence of micelle-forming surfactants and lipids.

Regula LK, Harris R, Wang F, Higgins CD, Koellhoffer JF, Zhao Y, Chandran K, Gao J, Girvin ME, Lai JR. Regula LK, et al. Among authors: lai jr. Biochemistry. 2013 May 21;52(20):3393-404. doi: 10.1021/bi400040v. Epub 2013 May 7. Biochemistry. 2013. PMID: 23650881 Free PMC article.

8

C-peptide inhibitors of Ebola virus glycoprotein-mediated cell entry: effects of conjugation to cholesterol and side chain-side chain crosslinking.

Higgins CD, Koellhoffer JF, Chandran K, Lai JR. Higgins CD, et al. Among authors: lai jr. Bioorg Med Chem Lett. 2013 Oct 1;23(19):5356-60. doi: 10.1016/j.bmcl.2013.07.056. Epub 2013 Aug 2. Bioorg Med Chem Lett. 2013. PMID: 23962564 Free PMC article.

9

Structural characterization of the glycoprotein GP2 core domain from the CAS virus, a novel arenavirus-like species.

Koellhoffer JF, Dai Z, Malashkevich VN, Stenglein MD, Liu Y, Toro R, S Harrison J, Chandran K, DeRisi JL, Almo SC, Lai JR. Koellhoffer JF, et al. Among authors: lai jr. J Mol Biol. 2014 Apr 3;426(7):1452-68. doi: 10.1016/j.jmb.2013.12.009. Epub 2013 Dec 12. J Mol Biol. 2014. PMID: 24333483 Free PMC article.

10

Influence of a heptad repeat stutter on the pH-dependent conformational behavior of the central coiled-coil from influenza hemagglutinin HA2.

Higgins CD, Malashkevich VN, Almo SC, Lai JR. Higgins CD, et al. Among authors: lai jr. Proteins. 2014 Sep;82(9):2220-8. doi: 10.1002/prot.24585. Epub 2014 May 6. Proteins. 2014. PMID: 24753307 Free PMC article.

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