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The NAD-dependent deacetylase SIRT2 is required for programmed necrosis.
Narayan N, Lee IH, Borenstein R, Sun J, Wong R, Tong G, Fergusson MM, Liu J, Rovira II, Cheng HL, Wang G, Gucek M, Lombard D, Alt FW, Sack MN, Murphy E, Cao L, Finkel T. Narayan N, et al. Among authors: sack mn. Nature. 2012 Dec 13;492(7428):199-204. doi: 10.1038/nature11700. Epub 2012 Nov 28. Nature. 2012. Retraction in: Nature. 2014 Feb 27;506(7489):516. doi: 10.1038/nature12897 PMID: 23201684 Retracted.
Restricted mitochondrial protein acetylation initiates mitochondrial autophagy.
Webster BR, Scott I, Han K, Li JH, Lu Z, Stevens MV, Malide D, Chen Y, Samsel L, Connelly PS, Daniels MP, McCoy JP Jr, Combs CA, Gucek M, Sack MN. Webster BR, et al. Among authors: sack mn. J Cell Sci. 2013 Nov 1;126(Pt 21):4843-9. doi: 10.1242/jcs.131300. Epub 2013 Sep 4. J Cell Sci. 2013. PMID: 24006259 Free PMC article.
Cyclophilin D modulates mitochondrial acetylome.
Nguyen TT, Wong R, Menazza S, Sun J, Chen Y, Wang G, Gucek M, Steenbergen C, Sack MN, Murphy E. Nguyen TT, et al. Among authors: sack mn. Circ Res. 2013 Dec 6;113(12):1308-19. doi: 10.1161/CIRCRESAHA.113.301867. Epub 2013 Sep 23. Circ Res. 2013. PMID: 24062335 Free PMC article.
The protein acetylase GCN5L1 modulates hepatic fatty acid oxidation activity via acetylation of the mitochondrial β-oxidation enzyme HADHA.
Thapa D, Wu K, Stoner MW, Xie B, Zhang M, Manning JR, Lu Z, Li JH, Chen Y, Gucek M, Playford MP, Mehta NN, Harmon D, O'Doherty RM, Jurczak MJ, Sack MN, Scott I. Thapa D, et al. Among authors: sack mn. J Biol Chem. 2018 Nov 16;293(46):17676-17684. doi: 10.1074/jbc.AC118.005462. Epub 2018 Oct 15. J Biol Chem. 2018. PMID: 30323061 Free PMC article.
146 results