Lu X - Search Results

1

Genome-Wide Analysis Unveils DNA Helicase RECQ1 as a Regulator of Estrogen Response Pathway in Breast Cancer Cells.

Lu X, Redon CE, Tang W, Parvathaneni S, Bokhari B, Debnath S, Li XL, Muys BR, Song Y, Pongor LS, Sheikh O, Green AR, Madhusudan S, Lal A, Ambs S, Khan J, Aladjem MI, Sharma S. Lu X, et al. Mol Cell Biol. 2021 Mar 24;41(4):e00515-20. doi: 10.1128/MCB.00515-20. Print 2021 Mar 24. Mol Cell Biol. 2021. PMID: 33468559 Free PMC article.

2

Replication stress induces specific enrichment of RECQ1 at common fragile sites FRA3B and FRA16D.

Lu X, Parvathaneni S, Hara T, Lal A, Sharma S. Lu X, et al. Mol Cancer. 2013 Apr 22;12(1):29. doi: 10.1186/1476-4598-12-29. Mol Cancer. 2013. PMID: 23601052 Free PMC article.

3

Identification of RECQ1-regulated transcriptome uncovers a role of RECQ1 in regulation of cancer cell migration and invasion.

Li XL, Lu X, Parvathaneni S, Bilke S, Zhang H, Thangavel S, Vindigni A, Hara T, Zhu Y, Meltzer PS, Lal A, Sharma S. Li XL, et al. Among authors: lu x. Cell Cycle. 2014;13(15):2431-45. doi: 10.4161/cc.29419. Cell Cycle. 2014. PMID: 25483193 Free PMC article.

4

Transcriptome guided identification of novel functions of RECQ1 helicase.

Lu X, Parvathaneni S, Li XL, Lal A, Sharma S. Lu X, et al. Methods. 2016 Oct 1;108:111-7. doi: 10.1016/j.ymeth.2016.04.018. Epub 2016 Apr 18. Methods. 2016. PMID: 27102625 Free PMC article.

5

Genome-wide investigations on regulatory functions of RECQ1 helicase.

Debnath S, Lu X, Lal A, Sharma S. Debnath S, et al. Among authors: lu x. Methods. 2022 Aug;204:263-268. doi: 10.1016/j.ymeth.2022.02.010. Epub 2022 Feb 26. Methods. 2022. PMID: 35231585 Free PMC article.

6

Transcriptional regulation by a RecQ helicase.

Debnath S, Lu X, Sharma S. Debnath S, et al. Among authors: lu x. Methods Enzymol. 2022;673:227-249. doi: 10.1016/bs.mie.2022.03.057. Epub 2022 Apr 18. Methods Enzymol. 2022. PMID: 35965009 Free PMC article.

7

RECQ1 expression is upregulated in response to DNA damage and in a p53-dependent manner.

Parvathaneni S, Lu X, Chaudhary R, Lal A, Madhusudan S, Sharma S. Parvathaneni S, et al. Among authors: lu x. Oncotarget. 2017 May 27;8(44):75924-75942. doi: 10.18632/oncotarget.18237. eCollection 2017 Sep 29. Oncotarget. 2017. PMID: 29100281 Free PMC article.

8

RECQ1 interacts with FEN-1 and promotes binding of FEN-1 to telomeric chromatin.

Sami F, Lu X, Parvathaneni S, Roy R, Gary RK, Sharma S. Sami F, et al. Among authors: lu x. Biochem J. 2015 Jun 1;468(2):227-44. doi: 10.1042/BJ20141021. Biochem J. 2015. PMID: 25774876 Free PMC article.

9

N-butylphthalide (NBP) ameliorated ischemia/reperfusion-induced skeletal muscle injury in male mice via activating Sirt1/Nrf2 signaling pathway.

Lu P, Li WP, Zhou BJ, Tian WZ, Lu X, Gao W. Lu P, et al. Among authors: lu x. Physiol Rep. 2024 Dec;12(23):e70149. doi: 10.14814/phy2.70149. Physiol Rep. 2024. PMID: 39614673

10

The first-in-class bispecific antibody IBI318 (LY3434172) targeting PD-1 and PD-L1 in patients with advanced tumors: a phase Ia/Ib study.

Ruan DY, Wei XL, Liu FR, Hu XC, Zhang J, Ji DM, Huang DZ, Zhao YQ, Pan HM, Liao WJ, Yang KY, Xu N, Lu XX, Chen YL, Zhang W, Zhou H, Zhao HY, Xu RH. Ruan DY, et al. Among authors: lu xx. J Hematol Oncol. 2024 Nov 29;17(1):118. doi: 10.1186/s13045-024-01644-4. J Hematol Oncol. 2024. PMID: 39614368 Clinical Trial.

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